Results 101 to 110 of about 832,170 (284)

Carbogen-Induced Respiratory Acidosis Blocks Experimental Seizures by a Direct and Specific Inhibition of Na_V1.2 Channels in the Axon Initial Segment of Pyramidal Neurons. [PDF]

J Neurosci, 2023
Hatch RJ, Berecki G, Jancovski N, Li M, Rollo B, Jafar-Nejad P, Rigo F, Kaila K, Reid CA, Petrou S.   +9 more
europepmc   +1 more source

Stimulated osteoclastic and suppressed osteoblastic activity in metabolic but not respiratory acidosis

, 1995
When bone is cultured in acidic medium produced by a reduced bicarbonate concentration ([HCO(3-)]), a model of metabolic acidosis, there is greater net calcium efflux than when the same decrement in pH is produced by an increased partial pressure of ...
D. A. Bushinsky
core   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Toward implementation of lactate compared with pH in fetal scalp blood sampling during labor: A clinical comparative single‐center study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Lactate and pH in fetal blood samples are moderately correlated (r = −0.53). For the StatStrip® Lactate 2, we propose a lactate cutoff value of ≥5.6 mmol/L based on the most optimal balance between sensitivity (78.1% [60.0–90.7%]) and specificity (79.2% [73.4–84.3%]).
Suzanne J. van Woudenberg, Ivonne Mijnheer, Marcel M. G. J. van Borren, Lian Roovers, Femi Janse   +4 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones. [PDF]

J Physiol
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Wu Y, Bravo E, Richerson GB.
europepmc   +2 more sources

In vitro metabolic and respiratory acidosis selectively inhibit osteoblastic matrix gene expression

, 1999
Clinically, a decrease in blood pH may be due to either a reduction in bicarbonate concentration ([H[Formula: see text]], metabolic acidosis) or an increase in[Formula: see text] (respiratory acidosis).
David A. Bushinsky, Kevin K. Frick
core   +1 more source

Fetal heart rate patterns associated with acidemia at fetal blood sampling during labor—An observational study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The Swedish fetal heart rate (FHR) classification from 2017 identifies most FHR patterns associated with fetal acidemia as non‐normal, according to fetal blood sampling (FBS) in immediate connection to the ongoing FHR pattern. However, long‐standing FHR patterns with non‐repetitive decelerations of the types severe variable and late warrant increased ...
Erika Gyllencreutz, Klara Gröndal, Desiré Malm, Kari Johansson, Malin Holzmann   +4 more
wiley   +1 more source

Experimental Extracorporeal Circulation System: A Pilot Study in Rats

Artificial Organs, EarlyView.
A miniature extracorporeal circulation (ECC) system was developed for reproducible rodent studies. This system incorporates an integrated heat exchanger and a silicone membrane oxygenator within a double‐lumen circuit, resulting in an ultralow priming volume of < 1.5 mL.
Akira T. Kawaguchi, Kaori Inukai, Mayuko Shibata, Gen T. Kawaguchi, Kazuaki Sato, Taiga Aburaya, Jacob Bergsland, Yoshiyuki Yamada   +7 more
wiley   +1 more source

Acid-Base Changes of Acute Hypoxic Respiratory acidosis in Rabbits

, 1978
Experimental acute respiratory acidosis is mostly induced by raising simply arterial carbon dioxide tension , clinical respiratory acidosis , however. is usually complicated with hypoxia. To induce hypoxic respiratory acidosis.
김전, 황상익, 김우겸
core  

Interaction of metabolic and respiratory acidosis with α and β-adrenoceptor stimulation in rat myocardium.

, 2012
International audienceBACKGROUND: The effects of acute respiratory versus metabolic acidosis on the myocardium and their consequences on adrenoceptor stimulation remain poorly described.
Jouffroy, Romain, Amour, Julien, Jobart-Malfait, Aude, Carillion, Aude, Feldman, Sarah, Biais, Matthieu, Riou, Bruno   +6 more
core   +1 more source