Results 31 to 40 of about 542,005 (160)

Transcription Factor FOSL1 Promotes Cisplatin Resistance in Non-Small Cell Lung Cancer Cells by Modulating the Wnt3a/β-Catenin Signaling through Upregulation of PLIN3 Expression

Frontiers in Bioscience-Landmark
Background: Lung adenocarcinoma (LUAD) is the most prevalent histological subtype of lung cancer, accounting for 45.3% of all cases and serving as a major cause of cancer-related mortality.
Wanning Tong, Jianjun Sun, Bin Shen, Yaohua Hu, Chenxing Wang, Min Rao, Jin Li, Delin Xia, Jiagui Dong, Hong Wang, Dongmei Zhu, Haibo Wu, Zhigang Cai   +12 more
doaj   +1 more source

S100A9 Regulated M1/M2 Macrophage Polarization in Interleukin-10-Induced Promotion of Malignant Pleural Effusion

Journal of Immunology Research, 2023
Interleukin-10 (IL-10) promotes the formation and development of malignant pleural effusion (MPE). Previous studies have elucidated the pathogenesis from the view of the immune-regulation function of CD4+ T-cells.
Xue-Bin Pei, Feng-Shuang Yi, Shu-Feng Dong, Qing-Yu Chen, Xin-Yu Shi   +4 more
doaj   +1 more source

Risk Factor Assessment and Predictive Modeling for Ventilator‐Associated Pneumonia: Design and Clinical Implementation of an Artificial Intelligence‐Enhanced Early Detection Framework Using Multisource Data Analytics

The Clinical Respiratory Journal
Introduction Ventilator‐associated pneumonia (VAP) is associated with poor patient outcomes. Early identification of high‐risk patients remains a major clinical challenge.
Jia Zhang, Yitong Wang, Yuwei Cao, Jiaxin Li, Shuangmei Dai, Yulin Li, Zhe Zhang, Xin Zhang, Rui Yang, Xinjun Zhang, Jichao Chen, Wailong Zou   +11 more
doaj   +1 more source

Case Report: Recurrence of Positive SARS-CoV-2 Results in Patients Recovered From COVID-19

Frontiers in Medicine, 2020
Background: Coronavirus disease 2019 (COVID-19) is spreading throughout the world. Limited data are available for recurrence of positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) results in patients with long duration of COVID-19 ...
Ren-zi Zhang, Ren-zi Zhang, Wang Deng, Wang Deng, Jing He, Jing He, Yu-yan Song, Chun-fang Qian, Qian Yu, Qian Yu, Dao-xin Wang, Dao-xin Wang   +11 more
doaj   +1 more source

Effects of combining immune checkpoint inhibitors and anti-angiogenic agents on bone metastasis in non-small cell lung cancer patients

Human Vaccines & Immunotherapeutics, 2023
This study aimed to evaluate the efficacy of combining immune checkpoint inhibitors (ICIs) and anti-angiogenic agents in treating lung cancer patients with bone metastases (BMs), as it is unclear whether this combination is effective for this condition ...
Xiaohong Xie, Maolin Zhou, Liqiang Wang, Fei Wang, Haiyi Deng, Yiling Yang, Ni Sun, Ru Li, Ying Chen, Xinqing Lin, Ming Liu, Chengzhi Zhou   +11 more
doaj   +1 more source

Bronchoscopy and Pathology Findings in an Unusual Case of Allergic Bronchopulmonary Mycosis

Infectious Diseases & Immunity, 2021
. The diagnosis of allergic bronchopulmonary mycosis (ABPM) is usually made on clinical, serologic, and roentgenographic findings. However, the indicators in such diagnostic criteria still lack specificity, which results in a high rate of misdiagnosis. A
Yongqun Li, Caiyun Zhang, Chunyang Zhang, Haijuan Wang, Wei Zhao   +4 more
doaj   +1 more source

Transbronchial lung biopsy versus transbronchial lung cryobiopsy in critically ill patients with undiagnosed acute hypoxemic respiratory failure: a comparative study

BMC Pulmonary Medicine, 2022
Background In patients with acute hypoxemic respiratory failure whose diagnosis is not established after initial evaluation, obtaining a histopathological diagnosis may improve the patients’ prognosis.
Shiyao Wang, Yingying Feng, Yi Zhang, Ye Tian, Sichao Gu, Xiaojing Wu, Yiming Feng, Ling Zhao, Min Liu, Dan Wang, Ying Li, Zheng Tian, Shumeng Wang, Xu Huang, Guowu Zhou, Qingyuan Zhan   +15 more
doaj   +1 more source

Prevalence of respiratory pathogens during two consecutive respiratory syncytial virus seasons at a tertiary medical care center

Archivos Argentinos de Pediatria, 2019
To determine the etiological profiles of lower respiratory tract infection (LRI) in neonates during respiratory syncytial virus(RSV) season, and to define the clinical features of RSV-related infection and others.The retrospective study included newborn infants who were hospitalized for LRI during the two consecutive RSV seasons, and then tested for ...
Kiymet, Celik, Ozgur, Olukman, Hatice, Demirol, Demet, Terek, Gamze, Gulfidan, Ilker, Devrim, Pelin, Gulcu, Sertac, Arslanoglu, Sebnem, Calkavur   +8 more
openaire   +2 more sources

PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration

Cell Death and Disease, 2023
Extrachromosomal circular DNAs (eccDNAs) participate in tumorigenesis and tumor progression. However, the role and mechanism of eccDNAs have yet to be elucidated in non-small cell lung cancer (NSCLC).
Yongfeng Yang, Ying Yang, Hong Huang, Tingting Song, Shengqiang Mao, Dan Liu, Li Zhang, Weimin Li   +7 more
doaj   +1 more source

Feasibility of transbronchial lung cryobiopsy in patients with veno-venous extracorporeal membrane oxygenation support

ERJ Open Research, 2022
Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is essential life support in patients with severe acute hypoxaemic respiratory failure. However, biopsies should be considered for some patients with unknown aetiology.
Shiyao Wang, Guowu Zhou, Yingying Feng, Yi Zhang, Ye Tian, Sichao Gu, Xiaojing Wu, Meiyuan Li, Yiming Feng, Dan Wang, Ying Li, Zheng Tian, Ling Zhao, Min Li, Wenhui Chen, Xu Huang, Qingyuan Zhan   +16 more
doaj   +1 more source