Results 121 to 130 of about 5,091,665 (288)

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Correlation of sonographic and radiographic scores of lung edema and metrics of shunt, dead space, and respiratory mechanics in invasively ventilated patients

Objective: To investigate the relationship between sonographic and radiological scores of lung edema with metrics of shunt, dead space, and respiratory mechanics in critically ill patients under invasive ventilation for greater than 24 hours.
Bergmans, Dennis C.J.J., Filippini, Daan, Schnabel, Ronny M., Bos, Lieuwe D.J., Zimatore, Claudio, Biasucci, Daniele Guerino, Heijnen, Nanon F.L., Atmowihardjo, Leila, Schultz, Marcus J., Pisani, Luigi, Smit, Marry R., Hagens, Laura A., Bergmans, Dennis C. J. J., Heijnen, Nanon F. L., Bos, Lieuwe D. J.   +14 more
core   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Respiratory physiology after resupination following prone ventilation to predict 28-day mortality in mechanically ventilated patients: a machine learning analysis

Scientific Reports
The clinical significance of resupination parameters following prone positioning remains largely unknown. This study employed machine learning to predict the survival of patients receiving mechanical ventilation (MV) by analyzing oxygenation and ...
Lada Lijović, Tariq A. Dam, Moon Seong Baek, Tae Wan Kim, Gyungah Kim, Paul W. G. Elbers, Won-Young Kim, The Dutch ICU Data Sharing Collaborators   +7 more
doaj   +1 more source

Work of Breathing for Aviators: A Missing Link in Human Performance

Life
In this study, we explore the work of breathing (WoB) experienced by aviators during the Anti-G Straining Maneuver (AGSM) to improve pilot safety and performance. Traditional airflow models of WoB fail to adequately distinguish between breathing rate and
Victoria Ribeiro Rodrigues, Rheagan A. Pratt, Chad L. Stephens, David J. Alexander, Nicholas J. Napoli   +4 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Comparison of pressure control ventilation with volume control ventilation in patients undergoing spine surgery in prone position: An open label randomized controlled trial

The Indian Anaesthetists' Forum
Introduction: Evaluation and comparison of two modes of mechanical ventilation – volume control and pressure control in spine surgery in prone position in terms of respiratory mechanics (peak airway pressure [PAP], plateau pressure, lung compliance, dead
Poonam Godhwal, Renu Bala, Lalit Takia, Raj Singh   +3 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Effects on mechanical power of different devices used for inhaled sedation in a bench model of protective ventilation in ICU

Annals of Intensive Care
Background Inhaled sedation during invasive mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) has received increasing attention.
Pierre-Louis Pellet, Neven Stevic, Florian Degivry, Bruno Louis, Laurent Argaud, Claude Guérin, Martin Cour   +6 more
doaj   +1 more source