Results 21 to 30 of about 5,091,665 (288)

Intrapulmonary shunt and alveolar dead space in a cohort of patients with acute COVID-19 pneumonitis and early recovery [PDF]

, 2023
BACKGROUND: Pathological evidence suggests that COVID-19 pulmonary infection involves both alveolar damage (causing shunt) and diffuse micro-vascular thrombus formation (causing alveolar dead space).
Wagner, Peter D, Palmgren, Jenny,, Wagner, Peter D.,, Prisk, G. Kim, Palmgren, Jenny, Kairaitis, Kristina, Amis, Terence C, Wagner, Peter D., Farrow, Catherine E.,, Prisk, G Kim, Lindwall, Robert,, Hamzei, Sarah, Farrow, Catherine E, Lindwall, Robert, Hamzei, Sarah,, Amis, Terence C.,, Malhotra, Atul,, Harbut, Piotr, Malhotra, Atul, Hedenstierna, Göran,, Harbut, Piotr,, Farrow, Catherine E., Prisk, G. Kim,, Kairaitis, Kristina,, Amis, Terence C., Farrow, CE, Palmgren, J, Amis, TC, Harbut, P,, Lindwall, R,, Malhotra, A, Hedenstierna, G, Hedenstierna, Göran, Hamzei, S, Wagner, PD, Prisk, GK, Robert Lindwall, Jenny Palmgren, Catherine E. Farrow, G. Kim Prisk, Sarah Hamzei, Peter D. Wagner, Piotr Harbut, Terence C. Amis, Atul Malhotra, Goran Hedenstierna, Kristina Kairaitis   +46 more
core   +1 more source

Effect of Zolpidem and Enhanced Expiratory Rebreathing Space on Complex Sleep Apnea [PDF]

Sleep Medicine Research, 2011
Treatment-emergent central sleep apnea has been referred to as ‘complex sleep apnea’, where apparently obstructive respiratory events convert to central apneas with application of positive airway pressure.
Chang-Ho Yun, Robert J. Thomas
doaj   +1 more source

Chest wall loading during supine and prone position in patients with COVID-19 ARDS: effects on respiratory mechanics and gas exchange

Critical Care, 2022
Background Recent reports of patients with severe, late-stage COVID-19 ARDS with reduced respiratory system compliance described paradoxical decreases in plateau pressure and increases in respiratory system compliance in response to anterior chest wall ...
Michele Umbrello, Sergio Lassola, Andrea Sanna, Rocco Pace, Sandra Magnoni, Sara Miori   +5 more
doaj   +1 more source

Respiratory Physiology of Prone Positioning With and Without Inhaled Nitric Oxide Across the Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Severity Spectrum

Critical Care Explorations, 2021
IMPORTANCE:. Prone positioning improves clinical outcomes in moderate-to-severe acute respiratory distress syndrome and has been widely adopted for the treatment of patients with acute respiratory distress syndrome due to coronavirus disease 2019. Little
David R. Ziehr, MD, Jehan Alladina, MD, Molly E. Wolf, MD, Kelsey L. Brait, BS, Atul Malhotra, MD, Carolyn La Vita, RRT, Lorenzo Berra, MD, Kathryn A. Hibbert, MD, C. Corey Hardin, MD, PhD   +8 more
doaj   +1 more source

Relationship between D-dimers and dead-space on disease severity and mortality in COVID-19 acute respiratory distress syndrome: A retrospective observational cohort study [PDF]

, 2023
Background: Despite its diagnostic and prognostic importance, physiologic dead space fraction is not included in the current ARDS definition or severity classification. ARDS caused by COVID-19 (C-ARDS) is characterized by increased physiologic dead space
Worrall S., Retter A., Collins P., Barrett N. A., Gattinoni L., Busana M., Chiumello D., Camporota L., Sanderson B., Rose L., Ostermann M., Romitti F., Hunt B. J.   +12 more
core   +1 more source

End-tidal to arterial PCO2 ratio: a bedside meter of the overall gas exchanger performance

Intensive Care Medicine Experimental, 2021
Background The physiological dead space is a strong indicator of severity and outcome of acute respiratory distress syndrome (ARDS). The “ideal” alveolar PCO2, in equilibrium with pulmonary capillary PCO2, is a central concept in the physiological dead ...
Matteo Bonifazi, Federica Romitti, Mattia Busana, Maria Michela Palumbo, Irene Steinberg, Simone Gattarello, Paola Palermo, Leif Saager, Konrad Meissner, Michael Quintel, Davide Chiumello, Luciano Gattinoni   +11 more
doaj   +1 more source

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome [PDF]

, 2011
A study published in the previous issue of Critical Care demonstrates that measurement of the pulmonary dead-space fraction is superior to hypoxemia as an indicator of a favorable physiologic response to prone positioning in patients with severe acute ...
Matthay, Michael A, Kallet, Richard H, Richard H Kallet, Michael A Matthay   +3 more
core   +1 more source

Estimating Dead-Space Fraction for Secondary Analyses of Acute Respiratory Distress Syndrome Clinical Trials [PDF]

, 2015
OBJECTIVES: Pulmonary dead-space fraction is one of few lung-specific independent predictors of mortality from acute respiratory distress syndrome. However, it is not measured routinely in clinical trials and thus altogether ignored in secondary analyses
Beitler, Jeremy R, Liu, Kathleen D, Matthay, Michael A, Hayden, Douglas, Zhuo, Hanjing, Talmor, Daniel, Malhotra, Atul, Thompson, B Taylor, Spragg, Roger G   +8 more
core   +1 more source

Instrumental dead space in ventilator management

, 2021
Michela Botta and colleagues described ventilator management in a large cohort of patients with COVID-19 on mechanical ventilation.1 Their study provides important data on ventilator settings in this population and shows that high tidal volumes on the ...
Massimo Antonelli, Domenico Luca Grieco, Salvatore Maurizio Maggiore, Lellouche, François, François Lellouche, Maggiore, Salvatore Maurizio, Grieco, Domenico Luca, Antonelli, Massimo   +7 more
core   +1 more source

Effects of changes in trunk inclination on ventilatory efficiency in ARDS patients: quasi-experimental study

Intensive Care Medicine Experimental, 2023
Background Trunk inclination from semirecumbent head-upright to supine-flat positioning reduces driving pressure and increases respiratory system compliance in patients with acute respiratory distress syndrome (ARDS). These effects are associated with an
Martín H. Benites, David Torres, Fabian Poblete, Francisco Labbe, María C. Bachmann, Tomas E. Regueira, Leonardo Soto, Andrés Ferre, Jorge Dreyse, Jaime Retamal   +9 more
doaj   +1 more source