Results 111 to 120 of about 12,340,249 (385)

Breathing SPACE – a practical approach to the breathless patient. [PDF]

, 2016
Breathlessness is a common symptom which may have multiple causes in any one individual and causes which may change over time. Breathlessness campaigns encourage people to see their GP if they are unduly breathless.
Baxter, N, Hopkinson, NS
core   +1 more source

Long-term exposure to ambient ultrafine particles and respiratory disease incidence in in Toronto, Canada: a cohort study

Environmental Health, 2017
BackgroundLittle is known about the long-term health effects of ambient ultrafine particles (
S. Weichenthal, Li Bai, M. Hatzopoulou, Keith Van Ryswyk, J. Kwong, M. Jerrett, A. van Donkelaar, R. Martin, R. Burnett, Hong Lu, Hong Chen   +10 more
semanticscholar   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis [PDF]

, 2005
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis.
Gallimore, A, Lund, VJ, Paun, S
core   +1 more source

The Breathing, Thinking, Functioning clinical model: a proposal to facilitate evidence-based breathlessness management in chronic respiratory disease

npj Primary Care Respiratory Medicine, 2017
Refractory breathlessness is a highly prevalent and distressing symptom in advanced chronic respiratory disease. Its intensity is not reliably predicted by the severity of lung pathology, with unhelpful emotions and behaviours inadvertently exacerbating ...
A. Spathis, S. Booth, Catherine Moffat, R. Hurst, R. Ryan, Chloe Chin, J. Burkin   +6 more
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Phenotypic heterogeneity in mortality and prognosis of pulmonary alveolar proteinosis: a large-scale, global pooled analysis of individual-level data

Orphanet Journal of Rare Diseases
Background Pulmonary Alveolar Proteinosis (PAP) is a rare interstitial lung disease with diverse clinical manifestations and outcomes. However, there are limited data on the heterogeneity of PAP, as well as its prognosis, cause of death and genetic ...
Junfeng Huang, Shuojia Xie, Yuewen Gao, Zikai Lin, Zhe Xu, Jinsheng Lin, Linzhi He, Gengjia Chen, Ziwen Zheng, Zhixing Xu, Jingyan Chen, Jiaming Guo, Zhile Wu, Ailing Duan, Weizhan Luo, Xinyu Song, Shiyue Li   +16 more
doaj   +1 more source

Pulmonary Rehabilitation in Chronic Respiratory Diseases

, 2022
Ravindran Chetambath
openalex   +1 more source

A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database.

, 2004
BACKGROUND: The effectiveness of influenza vaccination against hospitalization and death can only ethically be assessed in observational studies. A concern is that individuals who are vaccinated are healthier than individuals who are not vaccinated ...
Cumberland, Phillippa, Cutts, Felicity T, Hall, Andrew J, Hodgson, Cathy R, Mangtani, Punam, Roberts, Jennifer A   +5 more
core   +1 more source

Effect of external PEEP in patients under controlled mechanical ventilation with an auto-PEEP of 5 cmH2O or higher. [PDF]

, 2016
In some patients with auto-positive end-expiratory pressure (auto-PEEP), application of PEEP lower than auto-PEEP maintains a constant total PEEP, therefore reducing the inspiratory threshold load without detrimental cardiovascular or respiratory effects.
Amodeo, Guido, Bernardini, Achille, Berruto, Francesco, Filippini, Matteo, Fiorillo, Marialinda, Grazioli, Michele, Lucangelo, U., Marsilia, Paolo F., Minelli, Cosetta, Natalini, Giuseppe, Pennestr\uec, Vincenzo, Peratoner, Alberto, Rosano, Antonio, Testa, Marco, Tinnirello, Andrea, Tuzzo, Daniele, Ventilab, Group   +16 more
core   +1 more source