Results 91 to 100 of about 2,315,184 (310)

Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis [PDF]

, 2005
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis.
Gallimore, A, Lund, VJ, Paun, S
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Idiopathic pleuroparenchymal fibroelastosis in a patient with pectus excavatum: an overlooked association

Asian Journal of Internal Medicine
Pleuroparenchymal fibroelastosis (PPFE) is a rare, progressive interstitial lung disease characterised by prominent upper lobe fibrosis and elastotic changes. Its aetiology remains unclear, with most cases classified as idiopathic.
K. Maduranga, A. P. D. Manodhya, S. Palihawadene, E. Perara   +3 more
doaj   +1 more source

Respiratory diseases [PDF]

Postgraduate Medical Journal, 1990
D G, James, O M, Sharma
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Airway Organoid Models as Pivotal Tools for Unraveling Molecular Mechanisms and Therapeutic Targets in Respiratory Diseases: A Literature Review

Therapeutics and Clinical Risk Management
Shu-Ping Jiang,1,* Bing-Qi Lin,1,* Xing-Qiang Zhou,2,* Min-Hua Li,1,* Zhen-Cheng Feng,1 Yue-Ying Qin,1 Shi-Qi Lin,1 Zi-Qing Zhou,1 Yang Peng,1 Lian Li1 1State Key Laboratory of Respiratory Disease, National Clinical ...
Jiang SP, Lin BQ, Zhou XQ, Li MH, Feng ZC, Qin YY, Lin SQ, Zhou ZQ, Peng Y, Li L   +9 more
doaj  

A rigorous statistical framework for spatio-temporal pollution prediction and estimation of its long-term impact on health [PDF]

, 2016
In the United Kingdom, air pollution is linked to around 40000 premature deaths each year, but estimating its health effects is challenging in a spatio-temporal study.
Lee, Duncan, Mukhopadhyay, Sabyasachi, Rushworth, Alastair, Sahu, Sujit K.   +3 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Noncommunicable Respiratory Disease and Air Pollution Exposure in Malawi (CAPS). A Cross-Sectional Study. [PDF]

, 2019
RationaleNoncommunicable respiratory diseases and exposure to air pollution are thought to be important contributors to morbidity and mortality in sub-Saharan African adults.ObjectivesWe set out to explore the prevalence and determinants of ...
Balmes, John, Burney, Peter, Flitz, Graham, Lesosky, Maia, Meghji, Jamilah, Mortimer, Kevin, Nightingale, Rebecca, Rylance, Sarah J   +7 more
core  

No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis [PDF]

, 2013
BACKGROUND: Mitochondrial dysfunction is an established feature of multiple sclerosis (MS). We recently described high levels of mitochondrial DNA (mtDNA) deletions within respiratory enzyme-deficient (lacking mitochondrial respiratory chain complex IV ...
Abadi A, Amy K Reeve, Brierley EJ, Broadwater L, Campbell GR, Campbell GR, Campbell GR, Campbell GR, Don J Mahad, Doug M Turnbull, Dutta R, Dutta R, Graham R Campbell, Harding AE, Horvath R, Iryna Ziabreva, Johnson MA, Krishnan KJ, Kumleh HH, Larsson NG, Mahler A, McFarland R, Murphy JL, Nociti V, Palace J, Parise G, Patte M, Rahman S, Rahman S, Reeve AK, Richard Reynolds, Sakiyama Y, Taylor RW, Verny C, Witte ME, Witte ME, Yu-Wai-Man P   +36 more
core   +2 more sources