Results 101 to 110 of about 12,844,909 (336)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Independent Information of Nonspecific Biomarkers in Exhaled Breath Condensate [PDF]

, 2010
Background: Exhaled breath condensate (EBC) has been used for diagnosing and monitoring respiratory disorders. For clinical purposes the assessment of easy-to-obtain nonspecific markers seems particularly interesting.
Behr, Jürgen, Dressel, Holger, Fischer, Rainald, Hohlfeld, Jens M., Huber, Rudolf M., Jörres, Rudolf A., Müller, Florian, Nowak, Dennis, Römmelt, Horst   +8 more
core   +1 more source

Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases

Pharmacological Research, 2020
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
D. H. Cheong, D. W. Tan, Fred W. S. Wong, T. Tran   +3 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Comparison of frailty in patients with nontuberculous mycobacterial lung disease and bronchiectasis: a prospective cohort study

BMC Pulmonary Medicine, 2022
Background The incidence of nontuberculous mycobacterial lung disease (NTM-LD) peaks in middle- and old age groups, coinciding with senescence; thus, chronic infectious diseases can accelerate frailty and worsen mental health in the elderly.
Kohei Fujita, Yutaka Ito, Yuki Yamamoto, Osamu Kanai, Takuma Imakita, Issei Oi, Takanori Ito, Zentaro Saito, Tadashi Mio   +8 more
doaj   +1 more source

Smart vest for respiratory rate monitoring of COPD patients based on non-contact capacitive sensing [PDF]

, 2018
In this paper, a first approach to the design of a portable device for non-contact monitoring of respiratory rate by capacitive sensing is presented.
Barbarov-Rostán, Gerardo, Cejudo Ramos, Pilar, Márquez, Martín, Eduardo, Naranjo Hernández, David, Ortega Ruiz, Francisco, Reina Tosina, Luis Javier, Roa Romero, Laura María, Talaminos Barroso, Alejandro   +7 more
core   +1 more source

Underlying respiratory diseases, specifically COPD, and smoking are associated with severe COVID-19 outcomes: A systematic review and meta-analysis

Respiratory Medicine, 2020
Background An outbreak of Corona Virus Disease 2019 (COVID-19) has spread rapidly reaching over 3 million of confirmed cases worldwide. The association of respiratory diseases and smoking, both highly prevalent globally, with COVID-19 severity has not ...
D. Sanchez-Ramirez, D. Mackey
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Severe Atelectasis due to Aspirated Valproic Acid Tablet

Case Reports in Pulmonology
A 60-year-old man treated with valproic acid (VPA) for epilepsy developed atelectasis and respiratory failure after an accidentally aspirated VPA tablet-induced mucus hypersecretion.
Tomomi Tanigaki, Takunori Ogawa, Sakika Nomura, Koki Ito, Yuhei Kurata, Akira Matsukida, Morio Ishihara, Aihide Yoshino, Akihiko Kawana, Yoshifumi Kimizuka   +9 more
doaj   +1 more source

Nasal delivery of H5N1 avian influenza vaccine formulated with GenJet™ or in vivo-jetPEI® induces enhanced serological, cellular and protective immune responses

Drug Delivery, 2018
Avian influenza virus infection is a serious public health threat and preventive vaccination is the most cost-effective public health intervention strategy.
Weiping Cao, Margarita Mishina, Samuel Amoah, Wadzanai P. Mboko, Caitlin Bohannon, James McCoy, Suresh K. Mittal, Shivaprakash Gangappa, Suryaprakash Sambhara   +8 more
doaj   +1 more source