Results 181 to 190 of about 1,166,270 (266)

From Promise to Practice: Harmonizing Telemedicine in Pediatric Chronic Respiratory Diseases. [PDF]

J Clin Med
Esposito S, Donà D, Brigadoi G, Campana BR.   +3 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Prevalence and Spatial Distribution of Chronic Respiratory Diseases in Dar es Salaam, Tanzania: Hydrological and Household Influences. [PDF]

Geohealth
Msuya I, Levira F, Moshi I, O'Dwyer J, Killeen GF.   +4 more
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Multi-omics to study chronic respiratory diseases and viral infections. [PDF]

Eur Respir Rev
Idrees S, Chen H, Sadaf T, Rehman SF, Johansen MD, Paudel KR, Liu G, Wang Y, Luecken MD, Hortle E, Philp AS, Budden KF, O'Rourke M, Kaiko GE, Lucas SEM, Dickinson JL, Allen PC, Powell JE, Zhang LY, Chambers DC, Corte T, Caramori G, Sauler M, Wark PA, Gote-Schniering J, Lehmann M, Conlon TM, Kapellos TS, Yildirim AÖ, Faner R, Dharmage SC, Wheelock CE, van den Berge M, Nawijn MC, Polverino F, Belz GT, Chotirmall SH, Segal LN, Faiz A, Hansbro PM.   +39 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Artificial Intelligence for the Diagnosis of Respiratory Diseases in Dogs and Cats: A Systematic Review. [PDF]

Vet Sci
Parrales-Bravo F, Jadán-Guerrero J, Medina-Castro K, Caicedo-Quiroz R.   +3 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Pertussis is identified among common respiratory diseases: A case report. [PDF]

SAGE Open Med Case Rep
Chen J, Wu Y, Tang J, Guo J, Zhai Y.
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source