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Acute respiratory distress syndrome [PDF]

open access: yesClinical Medicine, 2016
Acute respiratory distress syndrome is a common cause of acute respiratory failure that is underdiagnosed both inside and outside of intensive care units. Progression to the most severe forms of the syndrome confers a mortality rate greater than 40% and is associated with often severe functional disability and psychological sequelae in survivors. While
Mason, C, Dooley, N, Griffiths, M
openaire   +10 more sources

Expert consensus on the precise classification and diagnosis of acute respiratory distress syndrome

open access: yesZhongguo Linchuang Yixue
Acute respiratory distress syndrome (ARDS) is a common critical illness in clinical practice, with a high mortality rate. Given the limited traditional treatment options for ARDS and the high heterogeneity among patients, most clinical trials have failed
Expert Group for Precise Classification and Diagnosis of Acute Respiratory Distress Syndrome
doaj   +1 more source

Acute respiratory distress syndrome and acute lung injury in a trauma population with and without long bone fractures

open access: yesFrontiers in Systems Biology, 2023
Introduction: Trauma is the leading cause of death in persons under the age of 45. Recovery in patients who survive initial trauma are frequently complicated by sequelae of injury that increases susceptibility to infection and inflammation.
Julia L. Larson   +15 more
doaj   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman   +10 more
wiley   +1 more source

Respiratory Distress and Its Outcome among Neonates Admitted to Neonatal Intensive Care Unit of Mukalla Maternity and Child Hospital, Yemen

open access: yesDiyala Journal of Medicine, 2020
Background: Respiratory distress is one of the most common causes of admission in neonatal intensive care unit . Objective: To determine the causes and to study the various risk factors associated with development of respiratory distress and outcomes
Saleh Awad Bahwal   +2 more
doaj   +2 more sources

Acute respiratory distress syndrome [PDF]

open access: yesJournal of Clinical and Scientific Research, 2014
Acute respiratory distress syndrome (ARDS) is characterized by non-cardiogenic pulmonary oedema and respiratoy failure. In 1994, ARDS was defined by the American – European Consensus Conference (AECC) and since then issues regarding the reliability and
M.H. Rao   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Trends and advances in Leptospira, a bibliometric analysis

open access: yesFrontiers in Microbiology
BackgroundLeptospirosis is an acute zoonotic disease caused by pathogenic Leptospira, primarily transmitted to humans through contact with water or soil contaminated by the bacteria.
Wei Wang   +14 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Endothelial biomarkers (Von willebrand factor, BDCA3, urokinase) as predictors of mortality in COVID-19 patients: cohort study

open access: yesBMC Pulmonary Medicine
Background SARS-CoV-2 is a systemic disease that affects endothelial function and leads to coagulation disorders, increasing the risk of mortality.
Rocío Nayeli Sánchez-Santillán   +10 more
doaj   +1 more source

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