Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Ganciclovir for severe neonatal varicella pneumonia when acyclovir is unavailable: a case report. [PDF]
Shen Y, Qu S.
europepmc +1 more source
A novel de novo NSD2 variant (c.2137G>C, p.Gly713Arg) was identified in a Chinese patient presenting with a syndromic developmental disorder. RNA analysis from patient‐derived material revealed that this missense variant induces aberrant splicing of NSD2 transcripts, resulting in a frameshift and likely a loss‐of‐function protein product.
Shixuan Xu +7 more
wiley +1 more source
An algorithm to identify less invasive surfactant administration using a real-world database of preterm infants. [PDF]
Sun X +8 more
europepmc +1 more source
MYO6 and Heart: A Novel Variant in a Deaf Infant With Supraventricular Tachycardia
A novel homozygous frameshift variant in the MYO6 gene (c.2496_2497delAC; p.H833Qfs*5) was identified in a neonate presenting with bilateral congenital sensorineural hearing loss, paroxysmal supraventricular tachycardia (SVT), and prolonged QT interval.
Samira Kalayinia +5 more
wiley +1 more source
Lung ultrasound imaging can effectively monitor and guide treatment with pulmonary surfactant for preterm infants of pulmonary consolidation: a prospective observational cohort study. [PDF]
Zaili F, Na H.
europepmc +1 more source
Quantitative in vivo contrast‐enhanced UTE MRI enables sensitive and precise mapping of pulmonary surfactant distribution, revealing peripheral localization and homogeneous distal penetration under physiological conditions. Comparison with ex vivo models highlights the role of physiological processes in surfactant retention.
Oumaima Marfouk +9 more
wiley +1 more source
Impact of RSV Preventive Strategies on Hospitalizations for Bronchiolitis in Infants
ABSTRACT Introduction Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and hospitalization in infants. Since 2023, France has implemented two preventive strategies aimed at reducing RSV burden: long‐acting monoclonal antibody nirsevimab and RSV vaccine for pregnant women, the latter becoming available from September 2024.
Marine Tarizzo +7 more
wiley +1 more source
Research progress on biomarkers associated with neonatal respiratory distress syndrome. [PDF]
Xiong M, Deng J, Zhao J.
europepmc +1 more source
Palivizumab prophylaxis and risk of RSV infection among moderate-to-late preterm infants: A nationwide Korean cohort study from 2018 to 2022. [PDF]
So H +10 more
europepmc +1 more source

