Results 71 to 80 of about 640,649 (341)

High-frequency oscillatory ventilation in pediatric acute hypoxemic respiratory failure: disease-specific morbidity survival analysis. [PDF]

, 2012
BackgroundMultiple ventilatory strategies for acute hypoxemic respiratory failure (AHRF) in children have been advocated, including high-frequency oscillatory ventilation (HFOV).
Babbitt, Christopher J, Cooper, Michael C, Levine, Glenn K, Liao, Eileen, Nussbaum, Eliezer, Randhawa, Inderpal S   +5 more
core   +1 more source

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

New England Journal of Medicine, 2019
BACKGROUND The benefits of early continuous neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation remain unclear.
M. Moss, David T. Huang, R. Brower, N. Ferguson, A. Ginde, M. Gong, C. Grissom, S. Gundel, Douglas L. Hayden, R. D. Hite, P. Hou, C. Hough, T. Iwashyna, Akram Khan, Kathleen D. Liu, D. Talmor, B. Thompson, C. Ulysse, D. Yealy, D. Angus   +19 more
semanticscholar   +1 more source

Could SARS-CoV-2-Induced Hyperinflammation Magnify the Severity of Coronavirus Disease (CoViD-19) Leading to Acute Respiratory Distress Syndrome?

Frontiers in Immunology, 2020
Citation: Girija ASS, Shankar EM and Larsson M (2020) Could SARS-CoV-2-Induced Hyperinflammation Magnify the Severity of Coronavirus Disease (CoViD-19) Leading to Acute Respiratory Distress Syndrome? Front. Immunol. 11:1206. doi: 10.3389/fimmu.2020.01206
L. F. V. Dyk, A. Girija, E. Shankar, M. Larsson   +3 more
semanticscholar   +1 more source

Effectiveness of noninvasive ventilation in COVID‐19 related‐acute respiratory distress syndrome

Clinical Respiratory Journal, 2021
During this long COVID‐19 pandemic outbreak, continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) are being widely used to treat patients with moderate to severe acute respiratory failure (ARF). As for now, data on the efficacy of
F. Menzella, Chiara Barbieri, Matteo Fontana, Chiara Scelfo, C. Castagnetti, Giulia Ghidoni, P. Ruggiero, Francesco Livrieri, R. Piro, Luca Ghidorsi, G. Montanari, Giorgia Gibellini, Eleonora Casalini, F. Falco, C. Catellani, N. Facciolongo   +15 more
semanticscholar   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Sweet syndrome with pulmonary involvement in a patient with myelodysplastic syndrome [PDF]

, 2020
We report a patient with Sweet syndrome involving the pulmonary system in the context of myelodysplastic syndrome. Although Sweet syndrome may involve a variety of organ systems, the pulmonary system is rarely affected and can result in poor clinical ...
Bordelon, Jenna, Ho, Jonhan, James, Alaina, Karunamurthy, Arivarasan, Kazlouskaya, Viktoryia, Khosravi, Hasan, Mizes, Alicia, Patton, Timothy   +7 more
core  

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Paediatrics: how to manage acute respiratory distress syndrome

Drugs in Context, 2021
Background: Acute respiratory distress syndrome (ARDS) is a significant cause of mortality and morbidity amongst critically ill children. The purpose of this narrative review is to provide an up-to-date review on the evaluation and management of ...
Kam Lun Hon, Karen Ka Yan Leung, Felix Oberender, Alexander KC Leung   +3 more
doaj   +1 more source

Cyclic Strain and Macrophage‐Mediated Transport Govern Micron‐Sized PM2.5 Translocation across the Air–Blood Barrier

Advanced Science, EarlyView.
Using a dynamic, tri‐culture air‐blood barrier model, this study reveals that macrophage‐mediated transport governs micron‐sized particle translocation under cyclic strain. The process is highly size‐dependent that 2 µm particles are transported by macrophages, 0.2 µm particles diffuse passively, and 5 µm particles are effectively blocked.
Yongjian Li, Jinlong Xu, Zujie Gao, Haosheng Chen   +3 more
wiley   +1 more source