Results 141 to 150 of about 182,776 (202)

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The influence of chorioamnionitis on respiratory drive and spontaneous breathing of premature infants at birth: a narrative review. [PDF]

Eur J Pediatr
Panneflek TJR, Kuypers KLAM, Polglase GR, Derleth DP, Dekker J, Hooper SB, van den Akker T, Pas ABT.   +7 more
europepmc   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome. [PDF]

Crit Care
Baedorf-Kassis E, Murn M, Dzierba AL, Serra AL, Garcia I, Minus E, Padilla C, Sarge T, Goodspeed VM, Matthay MA, Gong MN, Cook D, Loring SH, Talmor D, Beitler JR, EPVent-2 Study Group.   +15 more
europepmc   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Assessment of Neural Respiratory Drive Using Surface Electromyography Parameters of Parasternal Muscles in Three Different Body Positions Among Healthy Young Adults: A Cross-Sectional Study. [PDF]

J Musculoskelet Neuronal Interact
Wakode S, Salkar P, Thakare A, Hulke S, Malhotra V, Jiwne R.   +5 more
europepmc   +1 more source

Soil Inorganic Electron Acceptors and Carbon Substrates Hierarchically Govern Wetland Methanogenesis Temperature Response

Advanced Science, EarlyView.
ABSTRACT Wetlands constitute Earth's largest natural methane (CH4) source, yet projections of their climate feedback remain uncertain due to poorly constrained temperature sensitivity (Q10‐CH4) of microbial methanogenesis. While water table dynamics have been demonstrated to regulate wetland methanogenesis by altering key soil conditions such as ...
Shuying Qiu, Qingfang Jing, Xuhui Zhou, Xiaoxin Sun, Zhenyu Wei, Baizhi Jiang, Hongyang Chen   +6 more
wiley   +1 more source

Bilateral phrenic nerve block to reduce hazardous respiratory drive in a mechanically ventilated patient with COVID-19-A case report. [PDF]

Clin Case Rep
Levis A, Gardill M, Bachmann KF, Berger D, Schandl C, Piquilloud L, Haenggi M.   +6 more
europepmc   +1 more source

D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats. [PDF]

Front Pharmacol, 2020
Moody OA, Zhang ER, Arora V, Kato R, Cotten JF, Solt K.   +5 more
europepmc   +1 more source