Results 91 to 100 of about 3,032,232 (303)

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Evaluation and Prevention of Perioperative Respiratory Failure

Respiratory failure is a common perioperative complication. The risk of respiratory failure can be reduced with effective preoperative evaluation, preventative measures, and knowledge of evidence-based management techniques.
Ashish K. Khanna, Jacqueline Palermo, Spencer Tingey, Scott Segal   +3 more
core   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Monaldi Archives for Chest Disease, 2016
Background and Aim. The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last ...
T. Kontakiotis, N. Manolakoglou, F. Zoglopitis, D. Iakovidis, L. Sacas, A. Papagiannis, A. Mandrali, D. Papakosta, P. Argyropoulou, D. Bouros   +9 more
doaj   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure [PDF]

, 2017
International audienceNoninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies.
Brozek Jan, Jaber, Samir, Mancebo, Jordi, Conti Giorgio, Raoof Suhail, Guntupalli, Kalpalatha, Jordi Mancebo, Stefano Nava, Paolo Navalesi, Hill Nicholas S., Guntupalli Kalpalatha, Sangeeta Mehta, Antonelli Massimo, Hill, Nicholas S., Rochwerg, Bram, Elliott, Mark, Hess Dean, Mehta Sangeeta, Giorgio Conti, Mancebo Jordi, Jaber Samir, Keenan Sean, Bram Rochwerg, Samir Jaber, Antonelli, Massimo, Suhail Raoof, Ferrer Miquel, Keenan, Laurent, Massimo Antonelli, Miquel Ferrer, Hill, Nicholas, Keenan, Sean, Jan Brozek, Navalesi, Paolo, Hess, Dean, Elliott, Mark W., Mark W. Elliott, Laurent Brochard, Rochwerg Bram, Nava Stefano, Dean Hess, Mehta, Sangeeta, Navalesi P, Brochard Laurent, Ferrer, Miquel, Brochard, Laurent, Sean Keenan, Raoof, Suhail, Nicholas S. Hill, Brozek, Jan, Conti, Giorgio, Nava, Stefano, Elliott Mark W., Kalpalatha Guntupalli   +53 more
core   +1 more source

Age and Sex Matter: Phenotypic Heterogeneity, Diagnostic Gaps, and Screening Tool Performance in Obstructive Sleep Apnea—A 10-Year Sleep Clinic Cohort Study

Diagnostics
Background: Obstructive sleep apnea (OSA) is a highly prevalent and heterogeneous sleep disorder. This study aimed to investigate age- and sex-specific phenotypes of OSA in a large clinical cohort, with special emphasis on the effects of aging and ...
Asterios Tzinas, Aliki Karkala, Serafeim-Chrysovalantis Kotoulas, Georgios Kalamaras, Eleni Mouloudi, Eleni Massa, Athanasia Pataka   +6 more
doaj   +1 more source

Respiratory Failure [PDF]

BMJ, 1960
openaire   +5 more sources