Results 231 to 240 of about 1,085,335 (335)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Safe spontaneous breathing with helmet noninvasive ventilation in acute hypoxemic respiratory failure. [PDF]

Curr Opin Crit Care
Rosà T, Menga LS, Ferreyro BL, Grieco DL, Antonelli M.   +4 more
europepmc   +1 more source

Multiple Organ Dysfunction in Children Mechanically Ventilated for Acute Respiratory Failure*

, 2017
Scott L. Weiss, Lisa A. Asaro, Heidi R. Flori, Geoffrey L. Allen, David Wypij, Martha A. Q. Curley   +5 more
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Respiratory Failure in Hyperthyroidism: Focus on Thyrotoxic Periodic Paralysis. [PDF]

Cureus
Tun T, Htay WY, Myat K.
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Unmasking MEGF10 Myopathy: A Rare Cause of Sudden Respiratory Failure in a Young Adult. [PDF]

Case Rep Neurol Med
Kleiser B, Hackenbruch L, Schittenhelm J, Bornemann A, Haack T, Grimm A, Martin P.   +6 more
europepmc   +1 more source

Endotheliopathy is Not Associated with Respiratory Failure But with Icu Admission and 30-Day Mortality in Community-Acquired Pneumonia – a Cohort Study

Martin Schønemann‐Lund, Theis Skovsgaard Itenov, Arnold Matovu Dungu, Maria Hein Hegelund, Camilla Koch Ryrsø, Rikke Krogh‐Madsen, Daniel Faurholt‐Jepsen, Morten H. Bestle, Birgitte Lindegaard   +8 more
openalex   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

Advanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong, Pietro Cataldi, Han Zhang, Emiliano Bilotti, Conor Boland, Athanassia Athanassiou, Dimitrios G. Papageorgiou   +6 more
wiley   +1 more source

Comparison of High Flow Nasal Oxygen Therapy with High Flow Nasal Oxygen Therapy Plus Non-invasive Ventilation for the Management of Acute Hypoxemic Respiratory Failure in Post-operative Patients – A Pilot Randomized Control Study

Маниша Шарма, FNU Sudipto, FNU Swati, Kumar Saurabh   +3 more
openalex   +1 more source