Results 41 to 50 of about 5,815,326 (246)

A Calibration Device to Compare Body Plethysmographs Among Pediatric Lung Function Laboratories

Frontiers in Physiology, 2018
Multi-center studies in specific airway resistance have shown significant inter laboratory variability. Comparison of plethysmographic equipment using a lung model easily transportable from one site to another should be of help to international normative
Bruno Demoulin, Iulia Ioan, Iulia Ioan, Claude Duvivier, Claude Bonabel, Cyril Schweitzer, Cyril Schweitzer, Cyril Schweitzer, François Marchal, François Marchal, Silvia Demoulin-Alexikova, Silvia Demoulin-Alexikova   +11 more
doaj   +1 more source

Early respiratory diagnosis: benefits of enhanced lung function assessment

BMJ Open Respiratory Research, 2021
Introduction The National Health Service for England Long Term Plan identifies respiratory disease as one of its priority workstreams. To assist with earlier and more accurate diagnosis of lung disease they recommend improvement in delivery of quality ...
Ravi Mahadeva, Karl P Sylvester, Luke Youngs, M A Rutter, Ross Beech   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Association between markers of respiratory morbidity in European children

, 2002
School-aged children often experience acute respiratory symptoms. In a multicentre European study, the association between chronic respiratory symptoms (reported in a questionnaire), skin-prick test results, and lung function, and the occurrence of acute
Brunekreef B, Timonen KL, Schwartz, J, Nielsen, Jörn,, Nielsen, Jörn, Brunekreef, B, Schwartz J, Timonen, KL, Lund University., Nielsen J   +9 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Parental education and children's respiratory and allergic symptoms in the Pollution and the Young (PATY) study.

, 2006
Inequalities in health between socio-economic groups are a major public health concern. The current authors studied associations between parental socio-economic status (SES) and children's respiratory and allergic symptoms in 13 diverse countries ...
Luttmann-Gibson, H, Galassi, C., Braun-Fahrländer, C., Antova, T, Slachtova, H., Fletcher, T, Kuzmin, SV, Heinrich, J, Hoek, G, Gehring, U, Kuzmin, S.V., Pattenden, S., Gehring, U., Moshammer, H., Heinrich, J., Galassi, C, Slachtova, H, Luttmann-Gibson, H., Rudnai, P, Fletcher, T., Antova, T., Fabianova, E., Zlotkowska, R, Hoek, G., Pattenden, S, Rudnai, P., Fabianova, E, Braun-Fahrländer, C, Moshammer, H, Zlotkowska, R.   +29 more
core   +1 more source

Bovine colostrum and immune function after exercise [PDF]

, 2012
Strenuous and/or prolonged exercise causes transient perturbations in immune function. It is well accepted that this is one mechanism contributing to the higher occurrence of infection (e.g.
Glen Davison, Davison, Glen
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source