Results 91 to 100 of about 433,563 (312)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Avaliação da função pulmonar após colecistectomias laparoscópicas e convencionais

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar a função pulmonar pós-colecistectomias laparoscópicas e subcostais abertas. MÉTODOS: Tratou-se de um ensaio randomizado, onde se avaliaram espirometrias pós-operatórias de dois grupos, cada qual com 15 pacientes.
Gilson Cassem Ramos, Edísio Pereira, Salustiano Gabriel Neto, Enio Chaves de Oliveira   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Contribution of four common pulmonary function tests to diagnosis of patients with respiratory symptoms: a prospective cohort study. [PDF]

, 2013
Background: Few studies of the diagnostic value of pulmonary function testing are available. We assessed the diagnostic contribution of four basic pulmonary function tests: spirometry, lung volume, airway resistance, and diffusing capacity.
Deman, René, Decramer, Marc, Van Renterghem, Dirk, Janssens, Wim, Joos, Guy, Marchand, Eric, Bogaerts, Kris, Belgian Pulmonary Function Study Investigators, Ninane, Vincent, Liistro, Giuseppe, Derom, Eric   +10 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Pulmonary function tests. [PDF]

, 2011
Pulmonary function tests are valuable investigations in the management of patients with suspected or previously diagnosed respiratory disease. They aid diagnosis, help monitor response to treatment and can guide decisions regarding further treatment and ...
Wilde, M, Ranu, H, Madden, B
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Evaluation of the respiratory symptoms and pulmonary function tests capacities in Yazd tile workers [PDF]

, 2011
Background: Tile workers are exposed to a lot of dusts and are susceptible to various pulmonary complications. This study was designed to evaluate the respiratory symptoms and lung capacities of tile workers.
H Hobobati, GH Halvani, R Jafari nodoushan, M Ebrahimzade   +3 more
core  

A study on respiratory problems and pulmonary function indexes among cement industry workers in Mashhad, Iran [PDF]

, 2015
Background: The respiratory system is the most vulnerable system in the cement industry. This study was conducted to determine the effects of occupational exposure to cement dust on the respiratory system more thoroughly.
Afshari Saleh, Lahya, Ehsan Rafeemanesh, Alizadeh, Ashkan, Zakeri, Hosein, Rafeemanesh, Ehsan, Ashkan Alizadeh, Hosein Zakeri, Lahya Afshari Saleh   +7 more
core   +1 more source