Results 71 to 80 of about 431,418 (311)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

EFFECT OF BREAST REDUCTION ON RESPIRATORY FUNCTION TESTS

, 2009
There are a few reports about effects of reduction mammaplasty on respiratory function tests with conflicting results. This study aims to investigate effects of reduction mammaplasty on respiratory function tests and contribute to solve the confusion on ...
Koken, Gulengul, Demir, Yavuz, Isler, Sukru, Tuzner, Murat, Turhan-Haktanir, Nurten, Yilmaz, Guray, Fidan, Fatma   +6 more
core   +1 more source

Evolution of cardiorespiratory interactions with age [PDF]

, 2013
We describe an analysis of cardiac and respiratory time series recorded from 189 subjects of both genders aged 16–90. By application of the synchrosqueezed wavelet transform, we extract the respiratory and cardiac frequencies and phases with better time ...
Iatsenko, D., Clarkson, P.B.M., Stefanovska, A., Owen-Lynch, P.J., Clarkson, Peter B. M., Bernjak, A., Shiogai, Yuri, Shiogai, Y., McClintock, P.V.E., Stankovski, Tomislav, Owen-Lynch, P. Jane, Stefanovska, Aneta, Iatsenko, Dima, McClintock, Peter V. E., Bernjak, Alan, Stankovski, T.   +15 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pulmonary function in women: comparative analysis of conventional versus single-port laparoscopic cholecystectomy

Revista do Colégio Brasileiro de Cirurgiões, 2018
Objective: to evaluate the pulmonary function of women submitted to conventional and single-port laparoscopic cholecystectomy. Methods: forty women with symptomatic cholelithiasis, aged 18 to 70 years, participated in the study.
MARISA DE CARVALHO BORGES, ALINE BORGES GOUVEA, STEPHANIA FERREIRA BORGES MARCACINI, PAULO FERNANDO DE OLIVEIRA, ALEX AUGUSTO DA SILVA, EDUARDO CREMA   +5 more
doaj   +1 more source

Lung function tests to monitor respiratory disease in preschool children

, 2018
Pulmonary function tests are routinely used in the diagnosis and follow-up of respiratory diseases. In preschool children assessment and evaluation of lung function has always been challenging but improved techniques that require only minimal ...
Lombardi E., Fainardi V.
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Pulmonary Function Tests and Work-Related Respiratory and Allergic

Iranian Journal of Allergy, Asthma and Immunology, 2009
Bakers are frequently exposed to various irritant chemicals during work which can induce respiratory problems. In this study, pulmonary function tests and self-reported respiratory and allergic symptoms in bakers were compared with matched control ...
Boskabady Mohammad Hosein, Taheri Ehsan, Ahmadi Sina, Ebrahimi Kolsoumeh, Soudaneh Malihe, Mohammadi Fatemeh, Sabourhasanzadeh Alireza   +6 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source