Results 61 to 70 of about 431,418 (311)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Respiratory symptoms and functions in barn workers

Annals of Agricultural and Environmental Medicine, 2014
Introduction and aim. The presented study was undertaken to investigate the respiratory health problems in family barns with one or more cows and at least one family member working in the barn. Methods.
Ege Gulec Balbay, Emine Banu Cakiroglu, Peri Arbak, Öner Balbay, Fatma Avcıoğlu, Abdullah Belada   +5 more
doaj  

Lung-function tests in neonates and infants with chronic lung disease: tidal breathing and respiratory control

, 2006
This paper is the fourth in a series of reviews that will summarize available data and critically discuss the potential role of lung-function testing in infants with acute neonatal respiratory disorders and chronic lung disease of infancy.
Pillow, J Jane, Frey, Urs, Urs Frey, J. Jane Pillow, David N. Baldwin, Stocks, Janet, Baldwin, David N, Janet Stocks   +7 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Lung Function Assessment by Impulse Oscillometry in Adults

Therapeutics and Clinical Risk Management, 2020
Noemi Porojan-Suppini, Ovidiu Fira-Mladinescu, Monica Marc, Emanuela Tudorache, Cristian Oancea Department of Pulmonology, Center for Research and Innovation in Personalized Medicine of Respiratory Diseases, University of Medicine and Pharmacy &ldquo ...
Porojan-Suppini N, Fira-Mladinescu O, Marc M, Tudorache E, Oancea C   +4 more
doaj  

Pulmonary Function Tests in Thunderstorm-associated Respiratory Symptoms: A Cross-sectional Study [PDF]

Iranian Journal of Medical Sciences
Background: Epidemic thunderstorm asthma is an observed increase in cases of acute bronchospasm following thunderstorms. This study aimed to compare the frequency of obstructive airway disease or bronchial hyperresponsiveness in subjects with ...
Maryam Haddadzadeh Shoushtari, Sakineh Afrakhteh, Seyed Hamid Borsi, Hanieh Raji, Esmaeil Idani   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Assembly 9:Allied respiratory professionals [PDF]

, 2016
Meet @ERS_Assembly9: allied respiratory professionals http://ow.ly/GRNY306ssOv Allied respiratory professionals are very important in daily clinical practice.
Russell, Anne Marie; id_orcid, Langer, D, Steenbruggen, I, York, Janelle, Steenbruggen, Irene, Makonga, J, York, J, Russell, A-M, Spruit, MA, Burtin, Chris, Russell, Anne Marie, Russell, Anne-Marie, Makonga, Jellien, Burtin, C, Langer, Daniel, Spruit, Martijn A., Yorke, Janelle   +16 more
core   +1 more source