Results 101 to 110 of about 2,309,617 (377)
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Türk Kardiyoloji Derneği Arşivi, 2014 Objectives: In this study, we evaluated the correlation between severity of deformity and cardiopulmonary function with regards to echocardiographic and spirometric findings.
Alper Hazım Gürsu +4 more
doaj +1 more source
Lung Lavage Cell Profiles in Diffuse Lung Disease [PDF]
, 2010 The standard armamentarium of tests that are used by pulmonologist are laboratory tests, pulmonary function tests, different radiological techniques (conventional chest-X rays, HRCT scans, etc) and pathohistological analyses of biopsies.
Silvana Smojver-Ježek +1 more
core +1 more source
Effect of endurance training on lung function: A one year study [PDF]
, 2005 The official published version can be accessed from the link below.Objective: To identify in a follow up study airway changes occurring during the course of a sport season in healthy endurance athletes training in a Mediterranean region.
Caillaud, C +5 more
core +2 more sources
T1 and T2-Weighted Magnetic Resonance Imaging of Respiratory Skeletal Muscles Correlates with Pulmonary Function Testing in Patients with Duchenne Muscular Dystrophy [PDF]
, 2021 Jacob A. Kaslow +3 more
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Monaldi Archives for Chest Disease, 2015 Background and Aim. Lung function abnormalities are the main factors responsible for the high mortality of cystic fibrosis (CF) patients. It is not yet clear whether Burkholderia cepacia infection causes more pronounced loss of lung function than ...
A.J. Lopes +5 more
doaj +1 more source
Subjective (CAT, MMRC) versus objective (PFT, 6MWD, SPO2) assessment in stable COPD patients [PDF]
Introduction:Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease that leads to morbidity and mortality in the world. The excess of investigation has shown that this illness is not confined only to the respiratory system ...
بیوک آقازاده, کاترین +3 more
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source