DFV890: a new oral NLRP3 inhibitor—tested in an early phase 2a randomised clinical trial in patients with COVID-19 pneumonia and impaired respiratory function [PDF]
Ildikó Madurka +99 more
openalex +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Components of respiratory function tests
The respiratory system is composed of the lungs, the conducting airways, the parts of the central nervous system concerned with the control of the muscles of respiration, and the chest wall [1]. The main functions of the respiratory system are to obtain oxygen from the external environment and supply it to the cells and to remove from the body the ...
MaiM Abdel-Aziz +1 more
openaire +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Spirometric Reference Equations for Elderly Chinese in Jinan Aged 60–84 Years
Background: The interpretation of spirometry varies on different reference values. Older people are usually underrepresented in published predictive values.
Xin-Yu Tian +7 more
doaj +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Background: The development of pulmonary complications after breast radiotherapy is still controversial. These complications might result in temporary or permanent damage to the lung.
Seyedeh Mahsa Abdemanafi +3 more
doaj +1 more source
The ecological impact of different mechanisms of chronic sub-lethal toxicity on feeding and respiratory physiology [PDF]
Sub-lethal toxicity tests, such as the scope-for-growth test, reveal simple relationships between measures of contaminant concentration and effect on respiratory and feeding physiology.
Willows, R.
core
Infant Pulmonary Function Testing: An Upcoming Modality for Evaluation of Respiratory Disorders [PDF]
Ankit Parakh, Paul Aurora
openalex +1 more source
The Effect of Respiratory Muscle Stretch Gymnastic (RMSG) on Pulmonary Function Test among Pregnant Ladies: An Experimental Study [PDF]
Khyati Bhambhi, Priyanshu Rathod
openalex +1 more source

