Results 41 to 50 of about 1,621,057 (276)

Monitoring of the Respiratory Muscles in the Critically Ill

American Journal of Respiratory and Critical Care Medicine, 2013
Abstract Evidence has accumulated that respiratory muscle dysfunction develops in critically ill patients and contributes to prolonged weaning from mechanical ventilation. Accordingly, it seems highly appropriate to monitor the respiratory muscles in these patients.
Doorduin, J., van Hees, H.W.H., van der Hoeven, J.G., Heunks, L.M.A., Heunks, L.M.A.   +4 more
openaire   +4 more sources

Development and validation of a machine learning model to predict early recurrence after surgery in NSCLC patients

Scientific Reports
To develop and validate a machine learning (ML) model for predicting early recurrence (ER) within two years post-surgery in non-small cell lung cancer (NSCLC) patients.
Guo-Yong Lin, Run-Nan Chen, Shun Wu, Zhi-Sen Gao, Xiang-Qiong Guo, Xiao-Hong Zheng, Shu-Zhen Chen   +6 more
doaj   +1 more source

Representativeness of the FluWatchers Participatory Disease Surveillance Program 2015–2016 to 2018–2019: How do participants compare with the Canadian population?

Canada Communicable Disease Report, 2021
Background: FluWatch is Canada’s national surveillance system that monitors the spread of influenza. Its syndromic surveillance component monitors the spread of influenza-like illness (ILI) in near-real time for signals of unusual or increased activity ...
Mireille Desroches, Liza Lee, Shamir Mukhi, Christina Bancej   +3 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

scRNA-seq revealed high stemness epithelial malignant cell clusters and prognostic models of lung adenocarcinoma

Scientific Reports
Lung adenocarcinoma (LUAD) is one of the sole causes of death in lung cancer patients. This study combined with single-cell RNA-seq analysis to identify tumor stem-related prognostic models to predict the prognosis of lung adenocarcinoma, chemotherapy ...
GuoYong Lin, ZhiSen Gao, Shun Wu, JianPing Zheng, XiangQiong Guo, XiaoHong Zheng, RunNan Chen   +6 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Estimation of the national disease burden of influenza-associated severe acute respiratory illness in Kenya and Guatemala : a novel methodology [PDF]

, 2013
Background: Knowing the national disease burden of severe influenza in low-income countries can inform policy decisions around influenza treatment and prevention.
Njuguna Henry, Mott, Joshua A., Kim A. Lindblade (265496), Henry Njuguna, Marc-Alain Widdowson, Mwanajuma Ngama (132330), Sonja J Olsen, Kim A Lindblade, Katz Mark A., Sidi Kazungu (382842), Joshua A. Mott (382843), Summers Aimee, McCracken John, Wences Arvelo, Sammy Khagayi, John McCracken, Khagayi Sammy, Kazungu Sidi, Aimee Summers (382838), Fuller James A., Marc-Alain Widdowson (123352), D. James Nokes (68994), Daniel R. Feikin (153640), Njuguna, Henry, Fuller, James A., Ngama, Mwanajuma, Daniel R Feikin, Joshua A Mott, Emukule Gideon, Sonja J. Olsen (226208), McCracken, John, Mark A. Katz (310324), Wences Arvelo (358137), Kazungu, Sidi, Mark A Katz, Nivaldo Linares-Perez, Nivaldo Linares-Perez (382840), Nokes D. James, Katz, Mark A., Mott Joshua A., Arvelo Wences, Sidi Kazungu, Olsen Sonja J., Summers, Aimee, Feikin, Daniel R., Olsen, Sonja J., Mwanajuma Ngama, Henry Njuguna (319757), Lindblade Kim A., James A Fuller, John McCracken (382841), Gideon Emukule, James A. Fuller (382837), Linares-Perez Nivaldo, Nokes, D. James, Arvelo, Wences, Emukule, Gideon, Gideon Emukule (336782), Widdowson Marc-Alain, D James Nokes, Linares-Perez, Nivaldo, Khagayi, Sammy, Ngama Mwanajuma, Aimee Summers, Sammy Khagayi (382839), Widdowson, Marc-Alain, Lindblade, Kim A., Feikin Daniel R.   +67 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source