Results 41 to 50 of about 63,238 (298)

The effects of inspiratory muscle training in older adults [PDF]

, 2015
Purpose: Declining inspiratory muscle function and structure and systemic low-level inflammation and oxidative stress may contribute to morbidity and mortality during normal ageing.
Aznar-Lain, Belman, Borg, Bowling, Brooks, Bruunsgaard, Carey, Davis, DEAN E. MILLS, Dennis, Downey, Enright, Falaschetti, Febbraio, Freedman, Garcia-Rio, GRAHAM R. SHARPE, Greig, Ho, Huang, Huang, Illi, Jensen, Johnson, Johnson, Kharraz, Kregel, Kumar, Kyle, MICHAEL A. JOHNSON, Miller, Mills, Mills, Murphy, Phillips, Polkey, Ramirez-Sarmiento, Robertson, Romer, Romer, Takahashi, Tidball, Troosters, Washburn, Watsford, WILLIAM H. T. SMITH, Wolsk, YVONNE A. BARNETT   +47 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Individualized ventilatory management in patients with COVID-19-associated acute respiratory distress syndrome

Respiratory Medicine Case Reports, 2021
Due to the coronavirus disease 2019 pandemic, the number of coronavirus disease 2019-associated acute respiratory distress syndrome is rapidly increasing.
Hiroki Taenaka, Takeshi Yoshida, Haruka Hashimoto, Hirofumi Iwata, Yukiko Koyama, Akinori Uchiyama, Yuji Fujino   +6 more
doaj   +1 more source

Pneumotachometer counts respiration rate of human subject [PDF]

, 1964
To monitor breaths per minute, two rate-to-analog converters are alternately used to read and count the respiratory rate from an impedance pneumograph sequentially displayed numerically on electroluminescent ...
Graham, O.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Within-breath oscillometry for identifying exercise-induced bronchoconstriction in pediatric patients reporting symptoms with exercise

Frontiers in Pediatrics
BackgroundEvaluating oscillometry parameters separately for the inspiratory and expiratory breath phases and their within-breath differences can help to identify exercise-induced bronchoconstriction (EIB) in pediatric outpatients disclosing exercise ...
Mario Barreto, Chiara Veneroni, Mariaclaudia Caiulo, Melania Evangelisti, Pasquale Pio Pompilio, Maria Cristina Mazzuca, Giorgia Raponi, Jacopo Pagani, Pasquale Parisi   +8 more
doaj   +1 more source

How do clarinet players adjust the resonances of their vocal tracts for different playing effects

, 2005
In a simple model, the reed of the clarinet is mechanically loaded by the series combination of the acoustical impedances of the instrument itself and of the player's vocal tract. Here we measure the complex impedance spectrum of players' tracts using an
Fritz, Claudia, Wolfe, Joe
core   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source