Results 71 to 80 of about 1,026,837 (287)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

An application of pacemaker respiratory monitoring system for the prediction of heart failure

Respiratory Medicine Case Reports, 2019
Sleep-disordered breathing (SDB) is one of the most common complications among heart failure (HF) patients. Changes of respiratory patterns during the various stages in patients with HF have not been fully investigated.
Takashi Koyama, Masanori Kobayashi, Tomohide Ichikawa, Tadamasa Wakabayashi, Hidetoshi Abe   +4 more
doaj   +1 more source

Respiratory health and endotoxin: associations and modification by CD14/-260 genotype [PDF]

, 2011
Exposure to endotoxin has been associated with increased respiratory symptoms and decrements in lung function in occupational settings but little is known about the health effects of domestic exposure in adults.
Jarvis, D., Heederik, D., Svanes, C., M. Kogevinas, Dep IRAS, Norbäck D, D. Jarvis, J. P. Zock, Olivieri, Mario, Bakolis, I., Jarvis, D, C. M. Chen, on behalf of the Indoor group of the ECRHS, S. Guerra, D. Norback, G. Verlato, Norback, D., Bakolis I, Ramasamy, A, Svanes C, Jarvis D, Ramasamy A, Chen CM, J. Heinrich, Guerra, S., Chen, C.M., Chen, C. M., ?, ?, Castro-Giner, F., D. Heederik, null null, Kogevinas, M, Zock JP, Doekes, G., A. Nevalainen, VERLATO, Giuseppe, Nevalainen, A., HITEA Study Group (), Nevalainen, A, Chen, CM, Olivieri, M., Norbäck, D, Guerra, S, Svanes, C, Indoor Group of the ECRHS, I. Bakolis, Castro-Giner, F, Norbäck, Dan,, Kogevinas, M., Verlato, G., Heinrich, J, Risk Assessment of Toxic and Immunomodulatory Agents, Zock, JP, Bakolis, I, Olivieri, M, the Work Package 10 group of HITEA, Heinrich, J., Guerra S, Zock, J. P., Zock, J P, C. Svanes, Heinrich J, Kogevinas M, Chen, C M, Bakolis, I; id_orcid, A. Ramasamy, Verlato, G, Work Package 10 Group of HITEA, Nevalainen A, Doekes, G, Zock, J.P., G. Doekes, Doekes G, M. Olivieri, Heederick D, Ramasamy, A., Heederik, D, F. Castro-Giner   +77 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Research progress on electrical impedance tomography for perioperative respiratory management [PDF]

Jichu yixue yu linchuang
Electrical impedance tomography (EIT) is a non-invasive imaging technique that generates cross-sectional images of chest by measuring changes in impedance as electric currents passing through human body.
ZHAO Lun, Adelijiang·MAIMAITIMING, YU Xueyuan, WANG Chunmei, Tunisha·AIHEMAITI
doaj   +1 more source

A comparison of impedance boundary conditions for flow acoustics [PDF]

, 2013
Acoustic liners remain a key technology for reducing community noise from aircraft engines. The choice of optimal impedance relies heavily on the modeling of sound absorption by liners under grazing flows.
Gabard, G.
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Micro-impedance cytometry

, 2010
Electrical impedance spectroscopy is a non-invasive and label free technique that allows for rapid counting and characterisation of particles in suspension based on their response to applied AC potentials. In recent years, lab-on-a-chip technologies have
Bernabini, Catia
core   +1 more source

Evaluation of Bioelectrical Impedance Analysis for Identifying Overweight Individuals at Increased Cardiometabolic Risk:A Cross-Sectional Study [PDF]

, 2014
OBJECTIVE: To investigate whether bioelectrical impedance analysis could be used to identify overweight individuals at increased cardiometabolic risk, defined as the presence of metabolic syndrome and/or diabetes.DESIGN AND METHODS: Cross-sectional study
Lamb Maxine J. E., Christopher D Byrne, Wilson, J.F., Lamb, M.J.E., Wild, S.H., Lamb, Maxine J E, Byrne, Christopher D, Wild, Sarah H; id_orcid, Wilson James F., Byrne Christopher D., Sarah H Wild, James F Wilson, Wild Sarah H., Wilson, James F; id_orcid, Byrne, Christopher D., Maxine J E Lamb   +15 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source