Results 61 to 70 of about 196,023 (288)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Congenital acinar dysplasia: a lethal entity

Autopsy and Case Reports, 2019
Congenital acinar dysplasia is a lethal, developmental lung malformation resulting in neonatal respiratory insufficiency. This entity is characterized by pulmonary hypoplasia and arrest in the pseudoglandular stage of development, resulting in the ...
Sabrina Oneto, Robert J. Poppiti
doaj   +1 more source

Endovascular repair for acute traumatic transection of the descending thoracic aorta: experience of a single centre with a 12-years follow up [PDF]

, 2015
Background: Most blunt aortic injuries occur in the proximal proximal descending aorta causing acute transection of this vessel. Generally, surgical repair of the ruptured segment of aorta is associated with high rates of morbidity and mortality and in
Butrico, L, de Franciscis, S, GRANDE, RAFFAELE, Indolfi, C, Mastroroberto, P., Perri, P, Serra, R   +6 more
core   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Математические модели развития и компенсации гипоксических состояний при ишемической болезни сердца у лиц летного состава [PDF]

, 2019
The increase of pilots’ labor intensity caused by rapid development of flight technologies and increasing of complexity of combat missions faced by flight crew members increases the loads on organisms of flight personnel in general and in particular on
Аралова, Наталия Игоревна, Ключко, Олена Михайлівна, Машкін, Валерій Йосипович, Машкіна, Ірина Вікторівна   +3 more
core  

Serum 25-hydroxyvitamin D levels in hospitalized adults with community-acquired pneumonia [PDF]

, 2018
Introduction: Community‐acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to respiratory tract infections ...
Bool, British Thoracic Society Research Committee and the Public Health Laboratory Service, Charlson, Cukic, Fine, Gombart, Haan, Huang, Jolliffe, Kamen, Karonova, Kim, Kochanek, Lim, Liu, Lu, Luna, Mandell, Niederman, Pletz, Remmelts, Ross, Røysted, Schnoor, Schöttker, Toubi, Welte, Youssef   +27 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial

BMC Neurology, 2012
Background Motor neurone disease (MND) is a devastating illness which leads to muscle weakness and death, usually within 2-3 years of symptom onset.
McDermott Christopher J, Maguire Chin, Cooper Cindy L, Ackroyd Roger, Baird Wendy O, Baudouin Simon, Bentley Andrew, Bianchi Stephen, Bourke Stephen, Bradburn Mike J, Dixon Simon, Ealing John, Galloway Simon, Karat Dayalan, Maynard Nick, Morrison Karen, Mustfa Naveed, Stradling John, Talbot Kevin, Williams Tim, Shaw Pamela J   +20 more
doaj   +1 more source

Molecular diagnosis and novel genes and phenotypes in a pediatric thoracic insufficiency cohort

Scientific Reports, 2023
Thoracic insufficiency syndromes are a genetically and phenotypically heterogeneous group of disorders characterized by congenital abnormalities or progressive deformation of the chest wall and/or vertebrae that result in restrictive lung disease and ...
Alanna Strong, Meckenzie Behr, Carina Lott, Abigail J. Clark, Frank Mentch, Renata Pellegrino Da Silva, Danielle R. Rux, Robert Campbell, Cara Skraban, Xiang Wang, Jason B. Anari, Benjamin Sinder, Patrick J. Cahill, Patrick Sleiman, Hakon Hakonarson   +14 more
doaj   +1 more source

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Allolio, B., Reincke, Martin, Winkelmann, W., Würth, G.   +3 more
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