Results 221 to 230 of about 206,602 (306)

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu   +4 more
wiley   +1 more source

Intranasal booster drives class switching and homing of memory B cells for mucosal IgA response. [PDF]

open access: yesJCI Insight
Chen S   +23 more
europepmc   +1 more source

Elexacaftor–Tezacaftor–Ivacaftor Reduces Revision Sinus Surgery in People With Cystic Fibrosis

open access: yesThe Laryngoscope, EarlyView.
Elexacaftor–tezacaftor–ivacaftor (ETI) was associated with a significant decrease in the frequency and rate of endoscopic sinus surgeries in patients with cystic fibrosis. These findings suggest an improvement in CF‐related chronic rhinosinusitis outcomes following ETI and may influence future CF treatment decisions.
Amy Lin   +6 more
wiley   +1 more source

Intestinal and multiple organ transplantation [PDF]

open access: yes, 2000
Abu-Elmagd, K   +6 more
core  

Diagnosing Eosinophilic Chronic Rhinosinusitis in Excised Tissue Using Optical Coherence Tomography

open access: yesThe Laryngoscope, EarlyView.
This study evaluated whether optical coherence tomography (OCT) can quantify eosinophils in excised sinonasal tissue and diagnose eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). Counts of globules resembling eosinophils on OCT images strongly correlated with eosinophils per HPF on histology, with a cutoff of 45 globules on OCT imaging ...
Ido Badash   +6 more
wiley   +1 more source

Impact of nonpharmaceutical interventions on inflammatory diseases of the nose. [PDF]

open access: yesAnn Med
Dai L   +7 more
europepmc   +1 more source

Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management

open access: yesThe Laryngoscope, EarlyView.
In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra   +41 more
wiley   +1 more source

Mastoid Surgery Does Not Normalize Tympanometric Middle Ear Pressure in Children With Cholesteatoma

open access: yesThe Laryngoscope, EarlyView.
Conflicting mechanism‐based hypotheses have been used to promote selection of different approaches to management of the mastoid in order to optimize middle ear pressure homeostasis after removal of cholesteatoma. For example: (a) conservation of mastoid mucosa and opening of ventilation pathways endoscopically to normalize function, (b) removal of ...
Adrian L. James
wiley   +1 more source

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