Results 241 to 250 of about 208,910 (323)

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Cost‐Utility Analysis of Intracapsular and Extracapsular Techniques for Pediatric Tonsillectomy

open access: yesThe Laryngoscope, EarlyView.
Intracapsular coblation tonsillectomy (ICT) is more cost‐effective than extracapsular tonsillectomy (ECT) in pediatric patients, particularly for ambulatory procedures. In a prospective cohort of over 5000 cases, ICT was associated with lower costs and comparable or better quality‐adjusted life years, even when accounting for potential revision ...
Stephen R. Chorney   +2 more
wiley   +1 more source

Human Papillomavirus: Possible Mechanisms of Damage in Sinonasal Inverted Papilloma. [PDF]

open access: yesInt J Mol Sci
Guzmán-Romero AK   +5 more
europepmc   +1 more source

Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome

open access: yesThe Laryngoscope, EarlyView.
This study compares the microbiomes of adenoids and tonsils in pediatric OSAS patients and healthy controls using 16S rRNA sequencing. Significant differences were found in the tonsillar microbiome of OSAS patients, with lower alpha diversity and an overrepresentation of pathogenic genera like Haemophilus and Neisseria, while adenoid microbiomes showed
Oded Kraus   +7 more
wiley   +1 more source

<i>Ex vivo</i> mucosal cultures: an emerging player in vaccine development. [PDF]

open access: yesFront Cell Infect Microbiol
Chilakamarri N, Sallard E, Aydin M.
europepmc   +1 more source

C‐Reactive Protein Serum Values in Idiopathic and Autoimmune Subglottic Stenosis

open access: yesThe Laryngoscope, EarlyView.
This study characterized C‐reactive protein (CRP) levels in idiopathic and granulomatosis with polyangiitis‐related (GPA) subglottic stenosis (SGS) to assess CRP ability to distinguish SGS subtypes and predict recurrence. High CRP levels are more frequent in GPA‐SGS, potentially aiding clinical differentiation of etiologies.
Andrew J. Neevel   +6 more
wiley   +1 more source

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma   +7 more
wiley   +1 more source

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