A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
Advanced Science, EarlyView.This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Breathing pattern, accessory respiratory muscles work, and gas exchange evaluation for prediction of NIV failure in moderate-to-severe COVID-19-associated ARDS after deterioration of respiratory failure outside ICU: the COVID-NIV observational study. [PDF]
BMC Anesthesiol, 2022 Yaroshetskiy AI +7 more
europepmc +2 more sources
Reply to "Comprehensive work-up is warranted for patients with severe COVID-19 and muscle weakness including respiratory muscles". [PDF]
Clin Neurophysiol, 2021 Cabañes-Martínez L.
europepmc +1 more source
Advanced Science, EarlyView.Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu +10 more
wiley +1 more source
Effects of Whole-Body Electromyostimulation on the Thickness of Appendicular and Respiratory Muscles, Functionality, and Frailty in Patients From a Transitional Care Unit: A Randomized Clinical Trial Protocol. [PDF]
Physiother Res IntBorges ALP +7 more
europepmc +1 more source
Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity. [PDF]
Am J Pathol, 2021 Howard ZM +6 more
europepmc +1 more source
Advanced Science, EarlyView.Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang +9 more
wiley +1 more source
Advancements in imaging techniques for monitoring the respiratory muscles. [PDF]
Crit CareDres M +3 more
europepmc +1 more source
Comprehensive work-up is warranted for patients with severe COVID-19 and muscle weakness including respiratory muscles. [PDF]
Clin Neurophysiol, 2021 Finsterer J.
europepmc +1 more source
Advanced Science, EarlyView.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source