Results 51 to 60 of about 1,434,152 (273)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A dual effect of L-1-tosylamide-2-phenylethyl chloromethyl ketone on the respiratory metabolism of guinea pig phagocytes

, 1981
pubblicato su: Title(s): Bulletin européen de physiopathologie respiratoire. Other Title(s): Clinical respiratory physiology, 1980-1987 Clinical respiratory physiology Continues: Bulletin de physio-pathologie respiratoire Merged ...
Dri P, Zabucchi G, BELLAVITE, Paolo
core   +1 more source

An in silico analysis of oxygen uptake of a mild COPD patient during rest and exercise using a portable oxygen concentrator

International Journal of COPD, 2016
Ira Katz,1,2 Marine Pichelin,1 Spyridon Montesantos,1 Min-Yeong Kang,3 Bernard Sapoval,3,4 Kaixian Zhu,5 Charles-Philippe Thevenin,5 Robert McCoy,6 Andrew R Martin,7 Georges Caillibotte1 1Medical R&D, Air Liquide Santé International, Centre ...
Katz I, Pichelin M, Montesantos S, Kang MY, Sapoval B, Zhu K, Thevenin CP, McCoy R, Martin AR, Caillibotte G   +9 more
doaj  

Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology [PDF]

, 2019
The 2018 European Respiratory Society (ERS) International Congress held in Paris, France, served as a platform to discover the latest research on respiratory diseases, the improvement in their treatments and patient care.
Degani-Costa, Luiza Helena, Furian, Michael, Caballero, C., Turnbull, Christopher, Louvaris, Zafeiris, Almendros, Issac, Almendros, I., Furian, M., Baillieul, S., Turnbull, Christopher D., Turnbull, Christopher D, Degani-Costa, L.H., Hirotsu, C., Hirotsu, Camila, Louvaris, Z., Thiel, S., Turnbull, C.D., Thiel, Sira, Almendros, Isaac, Baillieul, Sébastien, Caballero-Eraso, Candela, Caballero, Candela, Furian M, Caballero C, Turnbull CD, Almendros I, Thiel S, Louvaris Z, Degani-Costa LH, Hirotsu C, Baillieul S   +30 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Applied respiratory physiology

, 2002
Respiratory failure, hypoxia with or without hypercarbia, is common in infants and children. Knowledge of the underlying abnormal physiology facilitates diagnosis and therapy.
Milner, A D, Greenough, A; id_orcid
core   +3 more sources

The influence of smoking on the formation of airway hyperresponsiveness to cold and the course of destructive-cytological processes in the goblet cells of the bronchial epithelium in patients with asthma

Бюллетень сибирской медицины, 2019
Tobacco smoking in patients with asthma can intensify the bronchi mucosa damage and significantly worsen the course of the disease.Aim. To assess the influence of tobacco smoking on the clinical manifestations of the disease, airway response to cold air ...
A. B. Pirogov, A. G. Prikhodko, V. P. Kolosov, Ju. M. Perelman   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Recent advances in respiratory muscle physiology and assessment

Recent advances in respiratory muscle physiology and assessment have enhanced our understanding of breathing mechanics, muscle adaptation and disease-related changes.
Aliverti, Andrea
core   +1 more source

Systems for the management of respiratory disease in primary care - an international series: United Kingdom [PDF]

, 2010
INTRODUCTION: The UK National Health Service (NHS) is essentially publicly funded through general taxation. Challenges facing the NHS include the rise in prevalence of long-term conditions and financial pressures.
Allison Worth, Mark Levy, Worth, Allison, Levy, Mark L., Fletcher, Monica, Pinnock, Hilary, Aziz Sheikh, Monica Fletcher, Hilary Pinnock, Pinnock, Hilary; id_orcid, Hoskins, Gaylor, Levy, Mark, Gaylor Hoskins, Sheikh, Aziz, Levy, Mark L   +14 more
core   +1 more source