Results 61 to 70 of about 239,545 (283)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

An in silico analysis of oxygen uptake of a mild COPD patient during rest and exercise using a portable oxygen concentrator

International Journal of COPD, 2016
Ira Katz,1,2 Marine Pichelin,1 Spyridon Montesantos,1 Min-Yeong Kang,3 Bernard Sapoval,3,4 Kaixian Zhu,5 Charles-Philippe Thevenin,5 Robert McCoy,6 Andrew R Martin,7 Georges Caillibotte1 1Medical R&D, Air Liquide Santé International, Centre ...
Katz I, Pichelin M, Montesantos S, Kang MY, Sapoval B, Zhu K, Thevenin CP, McCoy R, Martin AR, Caillibotte G   +9 more
doaj  

Instructional materials to teach airway reflexes: development of cordel literature and comics

Advances in Physiology Education
The respiratory system encompasses a complex network of neural mechanisms that regulate not only ventilation and gas exchange but also vital protective reflexes such as coughing, sneezing, and swallowing.
Ricardo Murilo Pereira Emídio, Êfeh Victório Monteiro Crempe, Josimary Morais Vasconcelos Oliveira, Roseli Soncini   +3 more
doaj   +1 more source

ERS International Congress 2023:highlights from the Respiratory Clinical Care and Physiology Assembly [PDF]

It is a challenge to keep abreast of all the clinical and scientific advances in the field of respiratory medicine. This article contains an overview of laboratory-based science, clinical trials and qualitative research that were presented during the ...
Drummond, David, Poberezhets, Vitalii, Vagheggini, G., Khurtsidze, E., Gonsard, Apolline, Barron, Sarah, Marillier, Mathieu, Latimer, L. E., Drummond, D., Kolekar, S., Gonsard, A., Franssen, F., Bayat, Sam, Franssen, Frits M.E., Vicente, C., Gille, Thomas, Vicente, Cláudia, Gille, T., Kaltsakas, Georgios, Pennati, F., Mekov, Evgeni, Khurtsidze, Elene, Bayat, S., Barron, S., Vogiatzis, I., Vontetsianos, A., Poberezhets, V., Pennati, Francesca, Vogiatzis, Ioannis, Kaltsakas, G., Sivapalan, Pradeesh, Latimer, Lorna E, Vontetsianos, Angelos, Kolekar, Shailesh, Marillier, M., Vagheggini, Guido, Mekov, E., Hui, Chi-Yan, Franssen, Frits M E, Latimer, Lorna, Castellana, G., Sivapalan, P., Castellana, Giorgio   +42 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Recent advances in respiratory muscle physiology and assessment

Recent advances in respiratory muscle physiology and assessment have enhanced our understanding of breathing mechanics, muscle adaptation and disease-related changes.
Aliverti, Andrea
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Computational physiological models for individualised mechanical ventilation: a systematic literature review focussing on quality, availability, and clinical readiness

Critical Care, 2023
Background Individualised optimisation of mechanical ventilation (MV) remains cumbersome in modern intensive care medicine. Computerised, model-based support systems could help in tailoring MV settings to the complex interactions between MV and the ...
R. S. P. Warnaar, M. P. Mulder, L. Fresiello, A. D. Cornet, L. M. A. Heunks, D. W. Donker, E. Oppersma   +6 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source