Results 211 to 220 of about 826,835 (308)

High-frequency oscillation improves mucus clearance and airway resistance in mechanically ventilated patients: a randomized clinical trial. [PDF]

Ann Intensive Care
Wang Y, Chen D, Xie W, Zhang R, Guo X, Wu H, Liu L, Yuan X.   +7 more
europepmc   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

A single compartment model to describe lung functionality: A comprehensive study. [PDF]

Physiol Rep
Al-Hetari HY, Al-Rumaima MA, Ghazi HH, Al-Naggar NQ, Ali EA, Alameri A.   +5 more
europepmc   +1 more source

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, EarlyView.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

Impact of breathing frequency on respiratory oscillometry measurements: a randomised cross-over and observational study of asthma patients. [PDF]

BMJ Open Respir Res
Knox-Brown B, Carozzo O, Sylvester KP.
europepmc   +1 more source

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

Advanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia, Martin J. Graves, Mary McLean, Carolin Pirkl, Carola‐Bibiane Schönlieb, Timo Schirmer, Florian Wiesinger, Matthias J. Ehrhardt   +7 more
wiley   +1 more source

Phage characterization analysis in respiratory samples from infected patients based on metagenomic next-generation sequencing. [PDF]

Front Cell Infect Microbiol
Huang Y, Cai Q, Chen Y, Amutijiang D, Lu Y, Huang W, Li L.   +6 more
europepmc   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

Erratum: "Patients' perspectives on antimicrobial resistance in chronic respiratory disease: an AMR-Lung/European Lung Foundation global patient survey" Efthymia Papadopoulou, Dominic L. Sykes, Pieter Goeminne, Ana Machado, Dareen Marghlani, Lisa McNeil, Joyce Norwell, Cátia Paixão, Amelia Shoemark, Jeanette Boyd, Miquel Ekkelenkamp, Stephanie Thee and Anand Shah on behalf of AMR-Lung Clinical Research Collaboration. <i>ERJ Open Res</i> 2025; 11: 00271-2025. [PDF]

ERJ Open Res
europepmc   +1 more source

Effect of periodontal therapy on the oral microbiome and lung function: an intervention study. [PDF]

Front Cell Infect Microbiol
Røsland A, Amin H, Lie SA, Malinovschi A, Bunæs DF, Bertelsen RJ.   +5 more
europepmc   +1 more source