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Antibiotic Resistance in Nosocomial Respiratory Infections
Clinics in Laboratory Medicine, 2014Nosocomial respiratory infections are the most common acquired infections in patients with severe underlying conditions and are responsible for high morbidity and mortality in this patient population. Multidrug-resistant (MDR) pathogens are associated with hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP).
Gerald A, Denys, Ryan F, Relich
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Estimating central and peripheral respiratory resistance
Journal of Applied Physiology, 1978An analytic approach for fractionating total respiratory resistance into central (Rc) and peripheral (Rp) components is presented. In the analysis, linear regression equations relating the logarithm of the measured total resistance to the logarithm of frequency are derived for data spanning the frequency range 1–16 Hz. The computed slope and intercept
R L, Pimmel +3 more
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Fractionating respiratory resistance in young children
Journal of Applied Physiology, 1979Total respiratory resistance (Rrs) and the fraction of this resistance located peripherally, (Fp) were measured in a group of children (3--5 yr old). The technique used forced random noise to characterize the frequency dependence of effective resistance and an algorithm to compute Rrs and Fp from these data.
S P, Williams +4 more
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Partitioning of Respiratory System Resistance in Children with Respiratory Insufficiency
American Journal of Respiratory and Critical Care Medicine, 1999Using end-inspiratory airway occlusion, respiratory system resistance (Rrs) can be partitioned into a flow-resistive component (Rint), and an additional component (DeltaR), reflecting viscoelasticity and time constant inequalities. We studied flow and volume dependence of Rrs and its subdivisions (Rint and DeltaR) in 13 children, seven mechanically ...
A G, Kaditis +3 more
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Antimicrobial resistance in respiratory tract pathogens
Expert Review of Anti-infective Therapy, 2004Antimicrobial resistance has been a problem ever since the introduction of antimicrobial agents 60 years ago. Today, this problem is increasing so rapidly that the end of the antimicrobial era is being predicted. The increasing problems caused by antimicrobial resistance can be illustrated by those seen in bacterial pathogens that cause community ...
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Validation of Respiratory Resistance Measurements
ASME 2011 Summer Bioengineering Conference, Parts A and B, 2011The airflow perturbation device (APD) has been developed as a portable, easy to use, and rapid-response instrument for noninvasively measuring respiratory resistance in humans. However, the APD has limited data validating it against established techniques; moreover, a method does not exist to standardize resistance measurement outputs between APD units.
James Pan +4 more
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An analysis of respiratory drive components during flow-resistive respiratory loading
Annals of Biomedical Engineering, 1983Inspiratory flow-resistive loading normally causes an additional respiratory drive that limits the resistance-induced decrease in minute ventilation (load compensation). Occlusion pressures (P100) were measured during CO2 rebreathing with and without added inspiratory loads in normal persons and persons with obstructive sleep apnea (OSA). At each point
P H, Abbrecht +2 more
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Respiratory Infections Due to Drug-Resistant Bacteria
Infectious Disease Clinics of North America, 2010Pneumonia is the most common infection that is the leading cause of death. The increasing antimicrobial resistance in major respiratory pathogens such as Streptococcus pneumoniae, Staphylococcus aureus and gram-negative bacteria has severely restricted the treatment options.
Jae-Hoon, Song, Doo Ryeon, Chung
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Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021Amila K Nanayakkara, Kevin Outterson
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Disinfectants and antiseptics: mechanisms of action and resistance
Nature Reviews Microbiology, 2023Jean-Yves Maillard, Michael John Pascoe
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