Results 61 to 70 of about 27,072 (229)

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Coinfection of some respiratory viruses in cattle: An abattoir study

Onderstepoort Journal of Veterinary Research
To investigate the existence of bovine viral diarrhoea virus (BVDV), parainfluenza virus 3 (PIV-3) and respiratory syncytial virus (RSV) as well as its coinfections, a total of 420 pneumonic lung tissue samples were collected from slaughterhouses in ...
Intisar K. Saeed, Yahia H. Ali, Muaz Magzoub Abdellatif, Alaa Mustafa, Ahmad M. Abdel-Mageed   +4 more
doaj   +1 more source

Trueperella pyogenes–Associated Acute Pneumonia in Korean Native Calves

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Trueperella pyogenes can cause a wide range of suppurative infections, including urogenital and mammary infections, liver abscesses and pneumonia. This case report demonstrates Trueperella pyogenes as a primary cause of bovine respiratory disease in Korean native calves.
Min‐Jeong Ji, Youngjun Kim, Byoung‐Soo Kim, Jongho Kim, Kyoung‐Seong Choi   +4 more
wiley   +1 more source

The Non-Structural NS1 Protein Unique to Respiratory Syncytial Virus: A Two-State Folding Monomer in Quasi-Equilibrium with a Stable Spherical Oligome [PDF]

, 2013
Human respiratory syncytial virus (hRSV) is a major infectious agent that cause pediatric respiratory disease worldwide. Considered one of the main virulence factors of hRSV, NS1 is known to suppress type I interferon response and signaling, thus ...
Camporeale, Gabriela, de Prat Gay, Gonzalo, Pretel, Miguel Esteban   +2 more
core   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, Volume 36, Issue 31, 16 April 2026.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Structural Analysis of Human Respiratory Syncytial Virus P Protein: Identification of Intrinsically Disordered Domains [PDF]

, 2014
Human Respiratory Syncytial Virus P protein plus the viral RNA, N and L viral proteins, constitute the viral replication complex. In this report we describe that HRSV P protein has putative intrinsically disordered domains predicted by in silico methods.
Asara, John M., Guerrero, Manuel C., Libermann, Towia A., Simabuco, Fernando M., Ventura, Armando M., Zerbini, Luiz F.   +5 more
core   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah, Denver P. Linklater, Vassil Tzanov, Chaitali Dekiwadia, Sergey Rubanov, Phuc H. Le, Laleh Tafakori, Ranya Simons, Graeme Moad, Soichiro Saita, Takashi Yanagishita, Hideki Masuda, Vladimir Baulin, Natalie A. Borg, Elena P. Ivanova   +14 more
wiley   +1 more source

Bovine respiratory syncytial virus infection: clinical manifestations, pathogenesis and molecular epidemiology (review)

Ветеринария сегодня
Introduction. Bovine respiratory syncytial infection is widespread in all countries of the world, including the Russian Federation. The etiologic agent is Orthopneumovirus bovis, it belongs to the family Pneumoviridae, genus Orthopneumovirus.
S. V. Koteneva, A. G. Glotov, T. I. Glotova, Aleksey V. Nefedchenko   +3 more
doaj   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

Occurrence in sick animals and genetic heterogeneity of Siberian isolates of bovine respiratory syncytial virus (Pneumoviridae: Orthopneumovirus; BRSV) identified in the territories of the Ural, Siberian Federal District and the Republic of Kazakhstan

Вопросы вирусологии
Introduction. Bovine respiratory syncytial virus (Pneumoviridae: Orthornavirae, Orthopneumovirus; Bovine orthopneumovirus, Bovine respiratory syncytial virus, BRSV) is one of causative agents of respiratory diseases in animals.
Alexander G. Glotov, Anton G. Yuzhakov, Tatyana I. Glotova, Alexey V. Nefedchenko, Svetlana V. Koteneva, Alina K. Komina, Elena V. Zhukova   +6 more
doaj   +1 more source