Results 121 to 130 of about 8,893,093 (256)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Influenza A virus interferes with respiratory syncytial virus in mice and reconstituted human airway epithelium

Microbiology Spectrum
Epidemiological studies suggest that respiratory syncytial virus (RSV) and influenza A virus (IAV) might interfere with each other. Viral interference mainly relies on interferon production elicited by a first virus that reduces the replication of a ...
Shella Gilbert-Girard, Jocelyne Piret, Chantal Rhéaume, Julie Carbonneau, Nathalie Goyette, Christian Couture, Guy Boivin   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Viral etiology in infants hospitalized for acute bronchiolitis

The Turkish Journal of Pediatrics, 2014
Acute bronchiolitis is predominantly a viral disease. Respiratory syncytial virus is the most common agent, but other newly identified viruses have also been considered as causes.
Dilek Azkur, Eda Özaydın, Emine Dibek-Mısırlıoğlu, Emine Vezir, Duygu Tombuloğlu, Gülşen Köse, Can N Kocabaş   +6 more
doaj  

Human and bovine respiratory syncytial virus: Immunopathologic mechanisms

Veterinary Quarterly, 1991
Human respiratory syncytial virus (HRSV) is the major respiratory tract pathogen of infants and young children. Bovine respiratory syncytial virus (BRSV) is recognised as an important cause of respiratory tract disease in calves. Both of these viruses and their respective diseases share many similarities.
openaire   +2 more sources

Volatile Relay Biosensing and Mobile Phone Imaging for Detection of Influenza Virus

Advanced Functional Materials, Volume 36, Issue 74, 14 September 2026.
Detection of volatile organic compounds is performed via a coupled enzymatic assay with mobile phone detection of the signal. Specific application demonstrated herein is the detection of influenza virus, across multiple levels of biological complexity, up to patient‐derived samples.
Dante G. Andersen, Josefine H. Jakobsen, Mikkel Høj Nielsen, Shreyans Chatterjee, Detlef Michel, Jan Münch, Rüdiger Gross, Alexander N. Zelikin   +7 more
wiley   +1 more source

Modulation of immune responses by human paraininfluenza virus [PDF]

, 2007
Human Parainfluenza virus type 3 (HPIV3) is a key respiratory pathogen responsible for bronchiolitis, pneumonia and croup. The persistent nature of this virus and its ability to reinfect within a short space of time has led to successive failures in the ...
Noone, Cariosa
core   +2 more sources

Respiratory syncytial virus under 2 years of age: hospitalization trends and risk factors for severe disease – preliminary data from the Portuguese sentinel network

Portuguese Journal of Pediatrics
Introduction and Objectives: Respiratory Syncytial Virus (RSV) infection is an important cause of hospitalization in children under five years. A national RSV sentinel network was set up in Portugal in April 2021.
Ana R. Torres, Aryse Melo, Carlos Aniceto, Raquel Guiomar, Vânia Gaio, Teresa Bandeira, Inês Azevedo, Ana P. Rodrigues   +7 more
doaj   +1 more source

Asthma and Lung Function in School-Aged Children After Severe RSV-A and RSV-B Bronchiolitis, Is There Any Difference? [PDF]

Pediatr Pulmonol
ABSTRACT Introduction Human respiratory syncytial virus (HRSV) is a major cause of respiratory disease. It is classified into two antigenic subgroups. While several authors have studied the potential link between HRSV infection and later development of recurrent wheezing (RW) or asthma, no previous studies have assessed the role of HRSV subtypes.
Sánchez MA, López PA, García GT, Calvo C, Iglesias-Caballero M, Mas V, Casas I, García-García ML.   +7 more
europepmc   +2 more sources

The Baboon as a Model to Study Human Health and Complex Disease

American Journal of Primatology, Volume 88, Issue 9, September 2026.
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley   +1 more source