Results 121 to 130 of about 63,092 (214)

Immunoglobulin G Levels in Yemeni Preterm Newborns: Infant Factors Predominate

Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Background IgG levels in preterm infants play a crucial role in response to infection and inflammation. Infectious disease burden in the low‐income countries, such as Yemen, exacerbates the problem. The preterm infant's IgG sources are either maternal or fetal immune system.
Antar F. A. M. Al‐Badani, Jamil M. A. S. Obaid, Safana M. H. Al‐Sofi, Rahma A. S. Al‐Mansoub   +3 more
wiley   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

Acta Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik, Hua-Poo Su, Yacob Gomez Llorente, Rachel L. Palte, Daniel J. Klein, Robert P. Hayes, Sadie P. Antine, Guilermo A. Asmar-Rovira, Nicole Bertoletti, Noel J. Byrne, Brittany L. Carroll, Ciro D. Cordeiro, Kaylynn Curfman, James Dutko, Michael J. Eddins, Thierry Fischmann, Barani Govindarajan, Corey W. Hecksel, Thu Ho, Kaspar Hollenstein, Mee Ra Hong, Alan Hruza, Andrii Ishchenko, Maru Jaime-Garza, Matt J. Jaremko, Hayley L. Knox, James Kostas, Harini Krishnamurthy, Ioannis Manolaridis, Cameron L. Noland, Andrea T. Partridge, Sangita B. Patel, Paul Reichert, John C. Reid, Catarina Felisberto-Rodrigues, Chitra A. Shintre, Jennifer M. Shipman, Elakkiya Tamilselvan, Morgan E. Walker, Susanne N. Walker, Renjing Wang, Katharine M. Wright, Tien-Jui Yen, Byung-Kuk Yoo, Sandra B. Gabelli   +44 more
wiley   +1 more source

Applying Baculovirus Surface Display Technology for Influenza Cytokine Profiling, Serological Detection and Antiviral Screening

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng, Zheng Yu Phan, Chi‐Wei Wang, Ching‐Fen Shen, Ping‐Chung Kuo, Hao‐Ze Li, Yu‐Chan Chao, Chih‐Hsuan Tsai   +7 more
wiley   +1 more source

A Case for Anti‐IgE Vaccination

Allergy, Volume 81, Issue 6, Page 2001-2013, June 2026.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff, Zahra Gharailoo, Monique Vogel, Martin F. Bachmann   +3 more
wiley   +1 more source

Respiratory Syncytial Virus Transmission in Closed Community Settings That Include Children: A Systematic Review and Meta‐Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Respiratory syncytial virus (RSV) is a leading cause of severe respiratory infections in children and is predominantly acquired and spread in community settings such as households and early childhood education centres. This review aims to synthesise the available evidence on RSV transmission in closed community settings that include
Gemma L. Saravanos, Mari Takashima, Asmaa El‐Heneidy, Catherine King, Miroslava Ross, Anita Williams, Robert S. Ware, Philip N. Britton   +7 more
wiley   +1 more source

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst, Valérie Sankatsing, Caterina Rizzo, Francesco Baglivo, Elizabeth Button, Marta Carballal Mariño, María Garcés Sánchez, Christine Hagemann, Simon de Lusignan, Oliver Martyn, Marc Raes, Daan Van Brusselen, Joanne Wildenbeest, Sarah Hak, Foekje Stelma, Jojanneke van Summeren, on behalf of the RSV ComNet network   +16 more
wiley   +1 more source

Epidemiological characteristics of influenza A virus, influenza B virus, respiratory syncytial virus, human rhinovirus, adenovirus and Mycoplasma pneumoniae infections in Henan, China. [PDF]

BMC Infect Dis
Xianchun M, Yuying L, Shijie Z, Qian C, Gaohui W, Wanhai W.   +5 more
europepmc   +1 more source

Factors associated with potentially inappropriate medication use, medication underuse and overuse in older adults in the German National Cohort

Journal of Internal Medicine, Volume 299, Issue 6, Page 754-775, June 2026.
Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Miriam Degen, Ulrike Haug, Oliver H. F. Scholle, Yaw Awuku‐Larbi, Sigrid Carlsson, Nina Ebert, Volker Harth, Anja M. Hauri, Margit Heier, Anne Herrmann, Michael Leitzmann, Jakob Linseisen, Claudia Meinke‐Franze, Nadia Obi, Phil Pendt, Thomas Reinhold, Barbara Thorand, Hermann Brenner, Ben Schöttker   +18 more
wiley   +1 more source

Is Clinical Outcome Pathogen Related? Characteristics and Outcomes of ICU Patients with Severe Acute Respiratory Infections: Focusing on Respiratory Syncytial Virus, Human Metapneumovirus, Influenza Virus, and Parainfluenza Virus. [PDF]

J Intensive Care Med
van der Bie S, Fluit RC, Neijzen T, Euser SM, van Gorp ECM, Kalpoe J, Souverein D, Snijders D, Du Toit J, Osterhaus ADME, Gommers D, van Lelyveld SFL, Goeijenbier M.   +12 more
europepmc   +1 more source

Heterogeneous Causes of Acute Respiratory Distress Syndrome Correlate With Distinct Peripheral Polyunsaturated Fatty Acid Metabolites

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Inflammatory insults, such as sepsis, pneumonia, aspiration, or trauma can trigger an inflammatory reaction leading to Acute Respiratory Distress Syndrome (ARDS). This study identified that different causes lead to differences in n−3 and n−6 polyunsaturated fatty acids (PUFAs) and their downstream oxylipins.
Laura A. Leuenberger, Joseph S. Bednash, Evangeline Schott, Carmen Mikacenic, Eric D. Morrell, Carson Richardson, Lynn A. Fussner, Jeffrey C. Horowitz, Rama K. Mallampalli, Saame Raza Shaikh, Robert M. Tighe, Kymberly M. Gowdy   +11 more
wiley   +1 more source