Results 121 to 130 of about 93,278 (240)

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Risk Factors and Medical Resource Utilization of Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza-Related Hospitalizations in Adults-A Global Study During the 2017-2019 Epidemic Seasons (Hospitalized Acute Respiratory Tract Infection [HARTI] Study). [PDF]

Open Forum Infect Dis, 2021
Falsey AR, Walsh EE, House S, Vandenijck Y, Ren X, Keim S, Kang D, Peeters P, Witek J, Ispas G.   +9 more
europepmc   +1 more source

Human Metapneumovirus: A Neglected Contributor to Acute Respiratory Infections in Bangladesh: A Public Health Perspective

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Acute respiratory tract infections (ARTIs) are a primary cause of mortality in Bangladesh, yet the Human Metapneumovirus (hMPV) remains critically underdiagnosed. This perspective aims to evaluate the current diagnostic landscape, identify specific surveillance gaps, and propose a prioritized strategic framework for ...
Abdullaha Al Mamun, K. A. M. Inzamul Islam   +1 more
wiley   +1 more source

Viral N 6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature Communications, 2019
Here, Xue et al. identify N 6-methyladenosine (m6A) modification sites in RNAs of respiratory syncytial virus (RSV) and show that these sites, particularly sites in the transcript encoding for the viral glycoprotein, affect virus replication in primary ...
Miaoge Xue, Boxuan Simen Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jianrong Li   +15 more
doaj   +1 more source

Human Metapneumovirus and Respiratory Syncytial Virus Disease in Children, Yemen

Emerging Infectious Diseases, 2006
Factors increasing the severity of respiratory infections in developing countries are poorly described. We report factors associated with severe acute respiratory illness in Yemeni children (266 infected with respiratory syncytial virus and 66 with human
Najla Al-Sonboli, Charles E. Hart, Nasher Al-Aghbari, Ahmed Al-Ansi, Omar Ashoor, Luis E. Cuevas   +5 more
doaj   +1 more source

Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]

, 2006
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Booth, C., Booy, R., Coen, P.G., Kaczmarski, E., Klein, N., Peckham, C., Stuart, J.M., Tully, J., Viner, R.M., Zambon, M.   +9 more
core  

Torque Teno Virus in Bronchoalveolar Lavage Fluid of Hematological Patients and Association With Pathogens

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Torque teno virus (TTV) replication is tightly modulated by the host immune response. As such, TTV viremia has been investigated as a biomarker of immune competence for monitoring the risks of allograft rejection and opportunistic infections in solid organ transplant recipients.
Mahdi Ouafi, Camille Cordier, David Beauvais, Serge Alfandari, Marie Titécat, Romain Dubois, Frédéric Wallyn, Séverine Loridant, Fanny Vuotto, Micha Srour, Céline Berton, Valérie Coiteux, Ibrahim Yakoub‐Agha, Boualem Sendid, Didier Hober, Enagnon Kazali Alidjinou   +15 more
wiley   +1 more source

Respiratory syncytial virus glycoproteins uptake occurs through clathrin-mediated endocytosis in a human epithelial cell line

Virology Journal, 2008
Cell-surface viral proteins most frequently enter the cell through clathrin or caveolae endocytosis. Respiratory syncytial virus antigen internalization by immune cells is via caveolin, however, uptake of paramyxovirus cell membrane proteins by non ...
Gómez-García Beatriz, Sánchez-Hernández Carla, Gutiérrez-Ortega Abel   +2 more
doaj   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core  

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source