Background. Acute respiratory tract infection (ARTI) is a significant cause of morbidity and mortality among children worldwide. The majority of acute respiratory infections in children are caused by viruses, with respiratory syncytial virus (RSV) being ...
Rana Farzi +3 more
doaj +1 more source
The Story behind the Science: On the discovery of respiratory syncytial virus
Respiratory syncytial virus (RSV) was discovered in 1956 by the laboratory of Robert Chanock after its isolation from children with upper respiratory infections.
Arturo Casadevall +3 more
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The Pneumonia Virus of Mice (PVM) Model of Acute Respiratory Infection
Pneumonia Virus of Mice (PVM) is related to the human and bovine respiratory syncytial virus (RSV) pathogens, and has been used to study respiratory virus replication and the ensuing inflammatory response as a component of a natural host— ...
Helene F. Rosenberg +4 more
doaj +1 more source
Spatial and Spatio-Temporal Distribution of Human Respiratory Syncytial Virus, Human Parainfluenza Virus, and Human Adenoviruses Cases in Kenya 2007-2013. [PDF]
Umuhoza T +3 more
europepmc +1 more source
The Use of Aerosolized Ribavirin in Respiratory Syncytial Virus Lower Respiratory Tract Infections in Adult Immunocompromised Patients: A Systematic Review [PDF]
Introduction: Respiratory syncytial virus (RSV)–associated lower respiratory tract infection (LRTI) is a concern in immunocompromised patients. Aerosolized ribavirin (RBV AER) is used for treatment of RSV LRTI; however, adverse events and rising drug ...
Avery, Lisa M. +2 more
core +2 more sources
Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems
Nasal delivery of mRNA using gellable aqueous biphasic systems (ABS) represents a noninvasive alternative while reducing the need for trained professionals and cold chain storage. Composed of gelatin, PEG, and water, these thermoresponsive hydrogels ensure controlled mRNA delivery and prolonged retention at the nasal mucosa, improving transfection ...
Bojan Kopilovic +4 more
wiley +1 more source
Morbidity burden, seasonality and factors associated with the human respiratory syncytial virus, human parainfluenza virus, and human adenovirus infections in Kenya. [PDF]
Umuhoza T +4 more
europepmc +1 more source
Protective Role for Itaconate During Inhaled Allergen Challenge
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source
Kawasaki Disease and Respiratory Viruses: Ecological Spatiotemporal Analysis
BackgroundKawasaki disease is an uncommon vasculitis affecting young children. Its etiology is not completely understood, although infections have been frequently postulated as the triggers.
Rana Sawires +4 more
doaj +1 more source

