Results 161 to 170 of about 136,544 (298)

Respiratory syncytial virus under 2 years of age: hospitalization trends and risk factors for severe disease – preliminary data from the Portuguese sentinel network

Portuguese Journal of Pediatrics
Introduction and Objectives: Respiratory Syncytial Virus (RSV) infection is an important cause of hospitalization in children under five years. A national RSV sentinel network was set up in Portugal in April 2021.
Ana R. Torres, Aryse Melo, Carlos Aniceto, Raquel Guiomar, Vânia Gaio, Teresa Bandeira, Inês Azevedo, Ana P. Rodrigues   +7 more
doaj   +1 more source

Respiratory syncytial virus glycoproteins uptake occurs through clathrin-mediated endocytosis in a human epithelial cell line

Virology Journal, 2008
Cell-surface viral proteins most frequently enter the cell through clathrin or caveolae endocytosis. Respiratory syncytial virus antigen internalization by immune cells is via caveolin, however, uptake of paramyxovirus cell membrane proteins by non ...
Gómez-García Beatriz, Sánchez-Hernández Carla, Gutiérrez-Ortega Abel   +2 more
doaj   +1 more source

Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects

Cell Proliferation, EarlyView.
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang, Zhong Chu, Shuwen Han, Yuefen Pan   +3 more
wiley   +1 more source

Respiratory Syncytial Virus Fusion Protein Promotes TLR-4–Dependent Neutrophil Extracellular Trap Formation by Human Neutrophils

PLoS ONE, 2015
Acute viral bronchiolitis by Respiratory Syncytial Virus (RSV) is the most common respiratory illness in children in the first year of life. RSV bronchiolitis generates large numbers of hospitalizations and an important burden to health systems ...
Giselle A. Funchal, N. Jaeger, R. Czepielewski, M. S. Machado, S. Muraro, R. Stein, C. Bonorino, B. Porto   +7 more
semanticscholar   +1 more source

Vaccination in dermatology 2025: Update considering current recommendations of the German Standing Committee on Vaccination

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt, Marc Schmalzing, Sophia Mohme, Matthias Goebeler   +3 more
wiley   +1 more source

Respiratory admissions and impact of COVID‐19 lockdowns for children with severe cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
In a population cohort of children with severe cerebral palsy, there was a reduced frequency of hospitalization for respiratory illness during periods of restricted social contact, implemented to reduce transmission of COVID‐19. This mirrored trends in the wider population and underlines the importance of community viral transmission in these children.
Susan M. Reid, Moya Vendeleur, Danielle Wurzel, Katherine Frayman, Joshua Osowicki, Kylie Crompton, Gordon Baikie, Giuliana Antolovich, Angela Guzys, Monica S. Cooper   +9 more
wiley   +1 more source

Viral etiology in infants hospitalized for acute bronchiolitis

The Turkish Journal of Pediatrics, 2014
Acute bronchiolitis is predominantly a viral disease. Respiratory syncytial virus is the most common agent, but other newly identified viruses have also been considered as causes.
Dilek Azkur, Eda Özaydın, Emine Dibek-Mısırlıoğlu, Emine Vezir, Duygu Tombuloğlu, Gülşen Köse, Can N Kocabaş   +6 more
doaj  

Recurrent c.‐11C>T change located upstream of the normal ATG initiation codon of ANKH causes self‐limited familial infantile epilepsy

Epilepsia, EarlyView.
Abstract Objective Pathogenic ANKH variants are a known cause of chondrocalcinosis (Online Mendelian Inheritance in Man [OMIM] #118600) and craniometaphyseal dysplasia (OMIM #123000). Here, we describe the phenotype and genotype of autosomal dominant infantile epilepsy caused by a c.‐11C>T change upstream of the gene's normal ATG initiation codon of ...
Josua Kegele, Hendrik Juenger, Harald Frantzmann, Dieter Gläser, Marc Sturm, Holger Lerche, Tobias B. Haack, Ingrid Bader   +7 more
wiley   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

Immunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho, Valéria Oliveira Silva, Luis Fernando de Macedo Brigido, Elizabeth De Gaspari   +3 more
wiley   +1 more source

The Kids Pain Collaborative: A Hybrid Type 3 Implementation Effectiveness Study Transforming Paediatric Pain Care in the Emergency Department

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate the impact of a participatory, action‐oriented implementation study, guided by the integrated Promoting Action on Research Implementation in Health Services framework, for optimising pain care processes in a tertiary paediatric emergency department. Design Hybrid type 3 implementation effectiveness.
Suzanne Williams, Samantha Keogh, David Herd, Sharonn Riggall, Roselyn Glass, Eugene Slaughter, Lee Jones, Clint Douglas   +7 more
wiley   +1 more source