A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe+14 more
core +1 more source
Prevalence of human respiratory syncytial virus circulating in Iran
Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection during early childhood and is associated with a great burden on patients, parents, and society. While no treatment is yet available, results from recent phase 2 clinical trials of cell-entry inhibitors and RSV vaccines are promising. To prepare for introduction of these
Salimi, Vahid+4 more
openaire +5 more sources
Paramyxoviruses: Respiratory Syncytial Virus and Human Metapneumovirus [PDF]
Human respiratory syncytial virus (RSV) and human metapneumovirus (MPV) are members of the family Paramyxoviridae of the Mononegavirales order, comprising the nonsegmented negative-strand RNA viruses. Paramyxoviridae has two subfamilies: Paramyxovirinae, which includes the parainfluenza viruses 1–4 and measles and mumps viruses, and Pneumovirinae ...
John V. Williams, James E. Crowe
openaire +2 more sources
Respiratory viruses in mechanically ventilated patients: a pilot study
Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with ...
Raquel Nazareth+10 more
doaj +1 more source
Identifying Cross-Utilization of RSV Vaccine Inventions across the Human and Veterinary Field
The respiratory syncytial virus (RSV) has two main variants with similar impact, a human and a bovine variant. The human respiratory syncytial virus (HRSV) is the most frequent cause of acute respiratory disease (pneumonia) in children, leading to ...
Marga Janse+3 more
doaj +1 more source
Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora+22 more
core +1 more source
Resurgence of Respiratory Syncytial Virus in Children: An Out-of-Season Epidemic in Portugal
Introduction: An out-of-season increase in respiratory syncytial virus (RSV) incidence was observed in Portugal from June 2021 onwards, revealing a continuing surge in cases throughout 2021/2022 autumn/winter.
Ana Rita Torres+5 more
doaj +1 more source
Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya [PDF]
Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in ...
Agoti, Charles N.+4 more
core +1 more source
The Story behind the Science: On the discovery of respiratory syncytial virus. [PDF]
Respiratory syncytial virus (RSV) was discovered in 1956 by the laboratory of Robert Chanock after its isolation from children with upper respiratory infections.
Casadevall A+3 more
europepmc +2 more sources
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state [PDF]
Human respiratory syncytial virus (RSV) is the main cause of lower respiratory tract infections in young children. The RSV fusion protein (F) is highly conserved and is the only viral membrane protein that is essential for infection.
Chen, Man+13 more
core +2 more sources