Results 1 to 10 of about 87,950 (268)

The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]

, 2009
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Charles Sande, D. James Nokes, Graham F. Medley, Gregory Fegan, Lisa F. P. Ng, Patricia A. Cane, Paul D. Scott, Rachel Ochola   +7 more
core   +8 more sources

Model evaluation of target product profiles of an infant vaccine against respiratory syncytial virus (RSV) in a developed country setting [PDF]

, 2020
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in children worldwide and is a significant cause of hospital admissions in young children in England.
Kinyanjui, Timothy, Nokes, D. James, Pan-Ngum, Wirichada, Saralamba, Sompob, Taylor, Sylvia, White, Lisa J.   +5 more
core   +1 more source

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens, Brian Gilbert, Cherrie AH, Connors M, Glezen WP, Kenny Roose, Koen Sedeyn, Liesbeth Vande Ginste, Lieselot Houspie, Marc Van Ranst, Michael Schotsaert, Mills JT, Nicholas JA, Nico Rooijen, Olmsted RA, Pedro Piedra, Sarah De Baets, Ventre K, Walter Fiers, Whitehead SS, Xavier Saelens   +20 more
core   +10 more sources

The natural history of respiratory syncytial virus in a birth cohort: the influence of age and previous infection on reinfection and disease. [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Cane, PA, Medley, GF, Nokes, DJ, Ochola, R, Ohuma, EO, Okiro, EA, Sande, CJ   +7 more
core   +2 more sources

Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]

, 2014
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia, Castellano, Verónica, Gentile, Ángela, Grobaporto, Marcela, Juárez, María del Valle, Lucion, María Florencia, Mistchenko, Alicia Susana, Romanin, Viviana Sandra, Viegas, Mariana   +8 more
core   +1 more source

Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya [PDF]

, 2012
Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear.
Alexander G. Mwihuri, Anderson, Cane, Cane, Cane, Cane, Cane, Charles J. Sande, Charles N. Agoti, Choi, Clayton O. Onyango, Collins, D. James Nokes, Falsey, Falsey, Glezen, Graham F. Medley, Gunson, Hall, Hall, Hall, Henderson, Johnson, Johnson, Melero, Mufson, Mufson, Nair, Nokes, Nokes, Ohuma, Okiro, Parveen, Patricia A. Cane, Peret, Peret, Posada, Sande, Scott, Sullender, Sullender, Tamura, Trento, Trento, Trento, Venter, Waris, White, Xia, Yamaguchi, Zlateva   +50 more
core   +1 more source

Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]

, 2004
For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core   +3 more sources

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +1 more source

Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort [PDF]

, 2015
BACKGROUND: Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and 'late preterm infants' may also be more susceptible to the ...
Adorni F, Agosti M, Arco A, Aurilia C, Barberi I, Barboni G, Bertino E, Boldrini A, Bonomi A, Bottau P, Braibanti S, Carlucci A, Corona MF, Corsello G, Corso G, Coscia A, Dall’Agnola A, De Curtis M, De Luca MG, Del Vecchio A, Di Fabio S, Di Santo S, Ellero S, Fabiano A, Fabris C, Faccia P, Faldella G, Fanos V, Gabriele B, Gargano G, Girardi E, La Forgia N, Ladetto L, Lanari M, Loprieno S, Macagno F, Magaldi R, Memo L, Molinari L, Musicco M, Natale F, Negri C, Ngalikpima CJ, Nicolini G, Nosari N, Orfeo L, Paolillo P, Parmigiani S, Piano F, Prinelli F, Puddu M, Rinaldi M, Romagnoli C, Sarnelli P, Scarcella A, Silvestri M, Spinelli M, Umbaldo A, Vandini S, Vuerich M, Zorzi G   +60 more
core   +1 more source

Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence [PDF]

, 2010
The severity of respiratory syncytial virus (RSV) infections appears to differ with age in both humans and bovines. A primary RSV infection in naïve infants and in young calves runs a more severe course when they are 1–6 months old than in their first ...
Antonis, A.F.G., Jong, M.C., de, Kimman, T.G., Most, R.G., van der, Poel, W.H.M., van der, Schrijver, R.S., Stockhofe-Zurwieden, N.   +6 more
core   +2 more sources