Viruses associated with pneumonia in adults. [PDF]
, 2012 Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core +1 more source
A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract [PDF]
PLoS Comput Biol. 2020 Apr 13;16(4):e1007705, 2019 Within the human respiratory tract (HRT), viruses diffuse through the periciliary fluid (PCF) bathing the epithelium, and travel upwards via advection towards the nose and mouth, as the mucus escalator entrains the PCF. While many mathematical models (MMs) to date have described the course of influenza A virus (IAV) infections in vivo, none have ...
arxiv +1 more source
Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]
, 2015 Background: Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.
Azziz Baumgartner, Eduardo +6 more
core +1 more source
Accurately summarizing an outbreak using epidemiological models takes time [PDF]
, 2023 Recent outbreaks of monkeypox and Ebola, and worrying waves of COVID-19, influenza and respiratory syncytial virus, have all led to a sharp increase in the use of epidemiological models to estimate key epidemiological parameters. The feasibility of this estimation task is known as the practical identifiability (PI) problem.
arxiv +1 more source
In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]
, 2007 We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Bonnet, Marion +5 more
core +1 more source
Shanghai yufang yixueObjectiveTo investigate the impact of acute respiratory infections in children under 12 years old in Pudong New Area， Shanghai from 2019 to 2023.MethodsAcute respiratory infection samples of children under 12 years old from three sentinel hospitals in ...
YUAN Yang +10 more
doaj +1 more source
Analyzing the dominant SARS-CoV-2 transmission routes towards an ab initio SEIR model [PDF]
, 2020 Identifying the relative importance of the different transmission routes of the SARS-CoV-2 virus is an urgent research priority. To that end, the different transmission routes, and their role in determining the evolution of the Covid-19 pandemic are analyzed in this work.
arxiv +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Resurgence of Respiratory Syncytial Virus Infections during COVID-19 Pandemic, Tokyo, Japan
Emerging Infectious Diseases, 2021 More than a year into the coronavirus-19 pandemic, intensified infection control measures have controlled most viral respiratory infections in Tokyo, Japan. As of July 2021, however, an unusually high number of respiratory syncytial virus infections were
Mugen Ujiie +3 more
doaj +1 more source
DeCom: Deep Coupled-Factorization Machine for Post COVID-19 Respiratory Syncytial Virus Prediction with Nonpharmaceutical Interventions Awareness [PDF]
arXiv, 2023 Respiratory syncytial virus (RSV) is one of the most dangerous respiratory diseases for infants and young children. Due to the nonpharmaceutical intervention (NPI) imposed in the COVID-19 outbreak, the seasonal transmission pattern of RSV has been discontinued in 2020 and then shifted months ahead in 2021 in the northern hemisphere.
arxiv