Complementary approaches to target human respiratory syncytial virus using small molecule ligands [PDF]
In the current project, situated at the interface of chemistry and virology, complementary drug discovery approaches (high-throughput screening and structurebased drug design) have been exploited in order to discover novel small molecule inhibitors of ...
Lardeau, Charles-Hugues Claude Jean
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Respiratory syncytial virus: current and emerging treatment options
Tiffany L Turner,1 Benjamin T Kopp,1 Grace Paul,1 Lindsay C Landgrave,2 Don Hayes Jr,1 Rohan Thompson11Department of Pediatrics, Ohio State University College of Medicine, 2Clinical Pharmacy, Nationwide Children's Hospital, Columbus, OH, USAAbstract:
Turner TL +5 more
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Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya [PDF]
Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in ...
Agoti, Charles N. +4 more
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The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]
There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Bett, Ann +11 more
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In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Mirandette, Carole +5 more
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Risk factors for respiratory syncytial virus bronchiolitis hospital admission in New Zealand. [PDF]
This study assessed risk factors for respiratory syncytial virus (RSV) hospitalization and disease severity in Wellington, New Zealand. During the southern hemisphere winter months of 2003--2005, 230 infants aged < 24 months hospitalized with ...
Rich, F. J. +21 more
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Respiratory Syncytial Virus Infection: From Biology to Therapy
Respiratory syncytial virus (RSV) is responsible for significant morbidity and mortality, particularly in infants younger than 18 months and in the elderly.
Shyam S. Mohapatra, PhD +1 more
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Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort [PDF]
The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in ...
G.F. Medley +11 more
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WHEEZE ASSOCIATED RESPIRATORY SYNCYTIAL VIRUS INFECTION AND ITS PREVENTION
Wheeze associated respiratory infection is an important cause of morbidity and mortality in both the developed and the developing worlds. The commonest causative agent is the Respiratory Syncytial Virus (RSV).
A Thaplial, U Ramachandran
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Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance [PDF]
Background.Although necessary for developing a rationale for vaccination, the burden of severe respiratory syncytial virus (RSV) disease in children in resource‐poor settings remains poorly defined.
Medley, GF +23 more
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