Results 21 to 30 of about 1,747,273 (202)

Cryo-EM structure of the respiratory syncytial virus RNA polymerase

Nature Communications, 2020
Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the
Dongdong Cao, Yunrong Gao, Claire Roesler, Samantha Rice, Paul D’Cunha, Lisa Zhuang, Julia Slack, Mason Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, Bo Liang   +13 more
doaj   +1 more source

Mothers' Knowledge and Practices Regarding Care of their Children with Respiratory Syncytial Virus [PDF]

Tanta Scientific Nursing Journal, 2023
Background: Respiratory syncytial virus is the chief cause of lower respiratory tractinfections in children which causes mild to severe symptoms. Aim: To assess mothers'knowledge and practices regarding care of their children with Respiratory Syncytial ...
Adel Abdelwahab, , Yahia Sayed, , Shimaa Younis   +2 more
doaj   +1 more source

Influence of age, severity of infection, and co-infection on the duration of respiratory syncytial virus (RSV) shedding [PDF]

, 2015
RSV is the most important viral cause of pneumonia and bronchiolitis in children worldwide and has been associated with significant disease burden. With the renewed interest in RSV vaccines, we provide realistic estimates on duration, and influencing ...
Agoti, Charles N., Munywoki, Patrick Kiio, Koech, Dorothy C., Kipkoech, J., Medley, Graham, Cane, Patricia, Nokes, D. James, Kibirige, N.   +7 more
core   +1 more source

Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence [PDF]

, 2010
The severity of respiratory syncytial virus (RSV) infections appears to differ with age in both humans and bovines. A primary RSV infection in naïve infants and in young calves runs a more severe course when they are 1–6 months old than in their first ...
Most, R.G., van der, Stockhofe-Zurwieden, N., Schrijver, R.S., Antonis, A.F.G., Poel, W.H.M., van der, Jong, M.C., de, Kimman, T.G.   +6 more
core   +1 more source

The epidemiology and severity of respiratory viral infections in a tropical country: Ecuador, 2009–2016

Journal of Infection and Public Health, 2019
Background: Respiratory viral infections (RVI) are a leading cause of mortality worldwide. We compared the epidemiology and severity of RVI in Ecuador during 2009–2016. Methods: Respiratory specimens collected within the national surveillance system were
Saverio Caini, Doménica de Mora, Maritza Olmedo, Denisses Portugal, María A. Becerra, Marcela Mejía, María C. Pacurucu, Jenny Ojeda, Guglielmo Bonaccorsi, Chiara Lorini, John Paget, Alfredo Bruno   +11 more
doaj   +1 more source

Epidemiological characteristics and phylogenic analysis of human respiratory syncytial virus in patients with respiratory infections during 2011–2016 in southern China

International Journal of Infectious Diseases, 2020
Background: Human respiratory syncytial virus (RSV) is one of the most important pathogens that cause acute respiratory infections in children and immunocompromised adults.
Hong-jiao Luo, Xu-bin Huang, Hui-ling Zhong, Cong-xiu Ye, Xin Tan, Kai Zhou, Lei Yuan, Su-fen Zhang, Xun Zhu, Cui-ji Lin, Wen-jun Wang, Lin Xu, Kai-yuan Cao   +12 more
doaj   +1 more source

Safety and immunogenicity of an intranasal sendai virus-based vaccine for human parainfluenza virus type I and respiratory syncytial virus (SeVRSV) in adults

Human Vaccines & Immunotherapeutics, 2021
SeVRSV is a replication-competent Sendai virus (SeV)-based vaccine carrying the respiratory syncytial virus (RSV) fusion protein (F) gene. Unmanipulated, non-recombinant SeV is a murine parainfluenza virus type 1 (PIV-1) and serves as a Jennerian vaccine
Felicia Scaggs Huang, David I. Bernstein, Karen S. Slobod, Allen Portner, Toru Takimoto, Charles J. Russell, Michael Meagher, Bart G. Jones, Robert E. Sealy, Christopher Coleclough, Kristen Branum, Michelle Dickey, Kristen Buschle, Monica McNeal, Mat Makowski, Aya Nakamura, Julia L. Hurwitz   +16 more
doaj   +1 more source

The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]

, 2009
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Nokes D. James, Ochola Rachel, Cane Patricia A., Scott, P. D. (Paul D.), Charles Sande, Medley Graham F., Fegan, Gregory, Scott, Paul D, Rachel Ochola, Greg Fegan, Cane, Patricia, Scott Paul D., Cane, Patricia A, Nokes, D. James, Paul D Scott, Sande Charles, Sande, Charles, Fegan Gregory, Medley, Graham F, Patricia A Cane, Fegan, Greg, D James Nokes, Ochola, Rachel, Medley, Graham, Graham F Medley, Nokes, D James, Gregory Fegan   +26 more
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The natural history of respiratory syncytial virus in a birth cohort : the influence of age and previous infection on reinfection and disease [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Medley, GF, Ochola, R., Nokes, D. James, Sande, CJ, Nokes, DJ, Ochola, R, Bottomley, C., Ohuma, EO, Okiro, E. A., Medley, Graham, Sande, C. J., Cane, Patricia, Okiro, EA, Ohuma, E. O., Cane, PA   +15 more
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Duration of shedding of respiratory syncytial virus in a community study of Kenyan children [PDF]

, 2010
Background: Our understanding of the transmission dynamics of respiratory syncytial virus (RSV) infection will be better informed with improved data on the patterns of shedding in cases not limited only to hospital admissions.
Lisa J White, Medley, GF, Nokes, D. James, Nokes, DJ, Ngama, Mwanajuma, Ngama, M, Patricia A Cane, White, Lisa, D James Nokes, White, L. J., Okiro, E. A., Emelda A Okiro, Medley, Graham, Graham F Medley, Cane, Patricia, Okiro, EA, Mwanajuma Ngama, Cane, PA   +17 more
core   +2 more sources