Results 61 to 70 of about 40,857 (208)

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

Internal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley, Philip George, Gemma Reynolds, Adam Stewart, Hang Quach, Nicole O'Leary, Zoe McQuilten, Andrea S. Henden, Lynette Chee, Chan Y. Cheah, Olivia Bupha‐Intr, Emily Blyth, Ben Teh, Monica Slavin, Michael Dickinson, Robert Weinkove   +15 more
wiley   +1 more source

Low Allergic Sensitisation in Wheezing Children With Down Syndrome: A Case–Control Study

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Respiratory disorders are frequent in children with Down syndrome (DS), causing prolonged hospitalisations and increased healthcare system costs. Among these, recurrent wheezing is common in these children despite indications of lower rates of allergic sensitisation and asthma.
Francylene Malheiros Macedo da Cunha Rego, Geórgia Veras de Araújo Gueiros Lira, Emanuel Sávio Cavalcanti Sarinho, Patricia Gomes de Matos Bezerra, Marcilio Lins Aroucha, Igor Gabriel Araujo Medeiros, Decio Medeiros Peixoto   +6 more
wiley   +1 more source

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

Nature Communications, 2017
Neutralizing antibodies for respiratory syncytial virus (RSV) can reduce disease in hospitalized children, but current options show limited efficacy.
Iebe Rossey, Morgan S. A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens   +13 more
doaj   +1 more source

Disparities in RSV Hospitalisations Among Children Under 2 Years in NSW, Australia

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To estimate RSV hospitalisation rates among children ≤ 2 years in New South Wales (NSW), Australia over two decades; to examine how rates varied by age, prematurity and selected co‐morbidities and to describe temporal, seasonal and geographic patterns in RSV hospitalisation across NSW.
Helen Soenong, Sadia Hossain, Ju‐Lee Oei, Sithum Munasinghe, Mithilesh Dronavalli, Evelyn Lee, Andrew Page, Kee Thai Yeo   +7 more
wiley   +1 more source

Virucidal Activity of the Drug «Thymogen®», a Nasal Dosed Spray, Against Human Respiratory Viruses In Vitro

Антибиотики и Химиотерапия
Background. Respiratory syncytial virus (RSV) and parainfluenza virus together account for up to 40% of the pathogens causing acute respiratory infections in children and adults.
V. S. Smirnov, V. V. Zarubaev, T. A. Kudryavtseva, I. L. Esaulkova, A. S. Volobueva, V. A. Zaplutanov, S. V. Petlenko   +6 more
doaj   +1 more source

Reactogenicity and Immunogenicity of RSV Vaccines in Immunocompromised Individuals With Hematological Malignancies

Transplant Infectious Disease, EarlyView.
In adults with hematologic malignancies, RSV vaccination was safe and induced antibody and T‐cell responses. However, antibody levels were lower and declined more rapidly than in healthy controls. While early immune responses were evident, reduced magnitude and durability of protection suggest the need for optimized vaccination strategies in this high ...
Alisse Hannaford, Zoe Swank, Simon D. van Haren, Natalie Izaguirre, Caitlin Syphurs, Zhou Lan, Bridget Yates, Urwah Kanwal, Grace Valentine, Ella Woehl, David Regan, Hannah Levine, Alexandra Tong, Maria Shehata, Fathia Oladipupo, Colleen Sedney, Kevin Ryff, Sanya Thomas, Joann Diray‐Arce, Xiaofang Li, Kimberly A. Dufresne, Lindsey A. Parisi, Aidan Eustace, Louise Hansen, David R. Walt, Ofer Levy, Amar Kelkar, Robert J. Soiffer, Vincent T. Ho, Lindsey R. Baden, Nicolas C. Issa, Ann E. Woolley, Amy C. Sherman   +32 more
wiley   +1 more source

Making Sense of Point‐Of‐Care Testing for the Acute Management of Respiratory Tract Infections in Young Children: Caregiver Experiences in Sweden

Acta Paediatrica, Volume 115, Issue 12, Page 2872-2879, December 2026.
ABSTRACT Aim This study examined how parents perceive and experience point‐of‐care testing in a paediatric emergency department and how these tests relate to the overall diagnostic process. Parents sought care for their children due to suspected respiratory tract infections. Methods Twenty parents participated in semi‐structured interviews.
Helle Mølsted Alvesson, Ingela Zenk, Reza Rasti, Tobias Alfvén   +3 more
wiley   +1 more source

Respiratory syncytial virus, infants and intensive therapy

Brazilian Journal of Infectious Diseases, 2012
The aims of this study were to determine the presence of respiratory syncytial virus (RSV) and to assess the clinical features of the disease in infants with acute low respiratory tract infection hospitalized at pediatric intensive care units (PICU) of ...
Ieda Aparecida Correa Bueno, Adriana Gut Lopes Riccetto, André Moreno Morcillo, Clarice Weis Arns, Emílio Carlos Elias Baracat   +4 more
doaj   +1 more source

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

Clinical Genetics, Volume 110, Issue 6, Page 736-741, December 2026.
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady, Hadar Hulin Ma'ayan, Michal Cohen, Karin Weiss   +3 more
wiley   +1 more source

Human Metapneumovirus and Respiratory Syncytial Virus, Brazil

Emerging Infectious Diseases, 2003
We describe the epidemiologic and clinical characteristics of 111 children attending clinics and hospitals in Aracaju, northeast Brazil, with acute respiratory infections attributable to human metapneumovirus (HMPV), respiratory syncytial virus (RSV), or
Luis E. Cuevas, Abubaker M. Ben Nasser, Winifred Dove, Ricardo Q. Gurgel, Julie Greensill, C. Anthony Hart   +5 more
doaj   +1 more source