Results 91 to 100 of about 16,243 (160)

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

open access: yesAdvanced Therapeutics, Volume 8, Issue 6, June 2025.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe   +4 more
wiley   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu   +11 more
wiley   +1 more source

Respiratory Syncytial Virus-Induced Acute Lung Injury in Adult Patients with Bone Marrow Transplants

open access: bronze, 1989
Marshall I. Hertz   +4 more
openalex   +1 more source

Comparison of Perceived Adverse Events After COVID‐19 Vaccination Between Pregnant and NonPregnant Women Using Two Cohort Studies in the Netherlands

open access: yesBirth Defects Research, Volume 117, Issue 6, June 2025.
ABSTRACT Background Maternal vaccines are upcoming. A clear picture of the adverse events (AEs) after maternal vaccination and whether this is comparable to a nonpregnant population is important. The objective of our study was to compare perceived AEs after COVID‐19 vaccination between pregnant and nonpregnant women and to study if it is feasible to ...
Petra J. Woestenberg   +4 more
wiley   +1 more source

Appearance of a Soluble Form of the G Protein of Respiratory Syncytial Virus in Fluids of Infected Cells

open access: bronze, 1987
David A. Hendricks   +3 more
openalex   +1 more source

Leukotrienes: Bridging the Inflammatory Gap in Asthma and Inflammatory Bowel Diseases (IBD)

open access: yesComprehensive Physiology, Volume 15, Issue 3, June 2025.
Dissecting the pathophysiological role of Leukotrienes in the lung–gut axis: A potential mediator of the asthma–IBD crosstalk. ABSTRACT Leukotrienes are potent inflammatory lipid mediators produced primarily by immune cells. Inflammation, being the center stone of two major disease conditions, namely, asthma and inflammatory bowel disease (IBD), has ...
Emma Elizabeth Sabu Kattuman   +4 more
wiley   +1 more source

Nirsevimab immunisation of infants and respiratory syncytial virus (RSV)‐associated hospitalisations, Western Australia, 2024: a population‐based analysis

open access: yes
Medical Journal of Australia, Volume 222, Issue 11, Page 568-570, June 2025.
Lauren E Bloomfield   +10 more
wiley   +1 more source

Splicing to keep splicing: A feedback system for cellular homeostasis and state transition

open access: yesClinical and Translational Medicine, Volume 15, Issue 6, June 2025.
ABSTRACT Background Alternative splicing (AS) plays a crucial role in regulating gene expression and governing proteomic diversity by generating multiple protein isoforms from a single gene. Increasing evidence has highlighted the regulation for pre‐mRNA splicing of the splicing factors (SFs).
Zhonghao Guo   +4 more
wiley   +1 more source

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