Results 101 to 110 of about 1,029,493 (234)

A reverse genetics approach to study the pathogenesis of pneumonia virus of mice [PDF]

Human and bovine respiratory syncytial viruses (HRSV and BRSV), along with pneumonia virus of mice (PVM) are the members of the genus Pneumovirus in the subfamily Pneumovirinae of the family Paramyxoviridae.
Sadigh, Yashar Mohammadzadeh
core  

Systematic Review and Meta‐Analysis Suggested That Neutrophils Predominated the Airways of Children With the Respiratory Syncytial Virus

Acta Paediatrica, EarlyView.
ABSTRACT Aim The respiratory syncytial virus (RSV) is a predominant aetiology of early‐life respiratory infections. This systematic review and meta‐analysis compared the cell types involved in airways inflammation in children with and without RSV, noting that immune responses can influence long‐term complications and may involve different inflammatory ...
Muhammad Pradhika Mapindra, Naz Chughtai, Muhammad Pradhiki Mahindra, Paul McNamara, Cissy Kartasasmita, Malcolm Gracie Semple, Mahendra Tri Arif Sampurna, Howard Clark, Jens Madsen   +8 more
wiley   +1 more source

Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic

Acta Paediatrica, EarlyView.
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley   +1 more source

BrECADD in three days: Implementation of a condensed intensive first‐line regimen in Hodgkin lymphoma

British Journal of Haematology, EarlyView.
BrECADD can be delivered over 3 days instead of four, reducing intravenous treatment days by 25% without compromising dose intensity. Among 30 patients with advanced‐stage Hodgkin lymphoma, no unexpected toxicity was observed; there were no early discontinuations, and 1‐year progression‐free and overall survival were both 100%.
Christian Peter Jaworek, Maja Supprian, Paul Jan Bröckelmann, Hishan Tharmaseelan, Justin Ferdinandus, Dennis A. Eichenauer, Anne Sophie Robertz, Janina Jablonski, Vincent Combüchen, Jan‐Oliver Staak, Karin Töpelt, Jan‐Michel Heger, Jon Rischewski, Jannik Stemler, Wolfram Klapper, Peter Borchmann, Bastian von Tresckow   +16 more
wiley   +1 more source

Mouse and Cotton Rat Models of Human Respiratory Syncytial Virus

, 2016
Human respiratory syncytial virus (hRSV) is a common respiratory virus that is usually no cause for alarm. Symptoms of hRSV usually resemble those of the common cold and can go undiagnosed.
Chen, Javier, Mahalingam, Suresh, Rudd, Penny   +2 more
core   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses. [PDF]

Emerg Microbes Infect, 2023
Raman SNT, Zetner A, Hashem AM, Patel D, Wu J, Gravel C, Gao J, Zhang W, Pfeifle A, Tamming L, Parikh K, Cao J, Tam R, Safronetz D, Chen W, Johnston MJW, Wang L, Sauve S, Rosu-Myles M, Domselaar GV, Li X.   +20 more
europepmc   +1 more source

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

Clinical Genetics, EarlyView.
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady, Hadar Hulin Ma'ayan, Michal Cohen, Karin Weiss   +3 more
wiley   +1 more source

Factors affecting respiratory syncytial virus positive wheezing illnesses in infants [PDF]

, 2002
Plan BObjective: Respiratory Syncytial Virus or RSV is the most common cause of lower respiratory tract infections in infants and young children. Often, the more severe the episode of RSV, the more likely wheezing will be present with the illness ...
Tarter, Erin Elizabeth Jahnke
core  

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, EarlyView.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source