Results 121 to 130 of about 77,284 (248)

The ARI etiology among children in Belarus in 2011-2012

open access: yesВопросы вирусологии, 2015
The seasonal distribution of the respiratory viruses for the period of 2011-2012 is presented. The ARI etiological structure among children 0-17 years, who were admitted to the hospital for respiratory disease in Belarus, was defined by the PCR-method ...
N. V. Gribkova   +5 more
doaj  

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

open access: yes, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens   +20 more
core   +3 more sources

Characteristics of the Long‐Term Care Data Cooperative: A New Resource for Research on Outcomes in Long‐Term Care

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The long‐term care (LTC) Data Cooperative is a National Institute on Aging‐funded data resource that links skilled nursing facility (SNF) electronic health record (EHR) data with Medicare and Medicaid claims for use in comparative effectiveness and interventional research.
Stephanie M. Kissam   +8 more
wiley   +1 more source

Factors associated with potentially inappropriate medication use, medication underuse and overuse in older adults in the German National Cohort

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Miriam Degen   +18 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Once‐Daily and Proactive Twice‐Weekly Roflumilast Cream 0.05% for Mild‐to‐Moderate Atopic Dermatitis in Children Aged 2–5 Years From a 52‐Week, Phase 3 Trial (INTEGUMENT‐OLE)

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield   +14 more
wiley   +1 more source

Development of allergy in children. I. Association with virus infections. [PDF]

open access: yes, 1979
Children born into allergic families, with two allergic parents, are at high risk of developing allergy within the first 5 years of life. In order to observe possible external factors in the sensitization process, a prospective study of 13 such children ...
Frick, OL, German, DF, Mills, J
core  

Joint Effects of Prenatal Antibiotics, Mode of Birth and Breastfeeding Duration on Childhood Infections: The Norwegian MoBa Cohort Study

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Prenatal antibiotic exposure and caesarean births are associated with an increased risk of hospitalised infection in children, but few studies have evaluated their impact on less severe infections and possible joint effects. Conversely, longer breastfeeding duration is protective against infections, but whether this effect varies ...
Isobel M. F. Todd   +4 more
wiley   +1 more source

The Effectiveness of the Palivizumab Programme in Reducing the Risk of Paediatric Asthma: A Population‐Based Study in Ontario, Canada

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Palivizumab was introduced in Canada in 1998 as a publicly funded programme to reduce respiratory syncytial virus (RSV) disease in high‐risk children. Severe early‐life RSV infections are associated with increased asthma risk. Thus, palivizumab may also indirectly reduce paediatric asthma.
Kimberley A. Foley   +9 more
wiley   +1 more source

Age at First RSV Hospitalisation and the Risk of Subsequent Bacterial Pneumonia

open access: yes
Acta Paediatrica, EarlyView.
Samuel Videholm   +4 more
wiley   +1 more source

Lung Biopsies in Patients Referred for Allogeneic Hematopoietic Cell Transplantation: Diagnostic Accuracy, Diagnostic Yield, and Clinical Utility

open access: yesTransplant Infectious Disease, EarlyView.
Among patients referred for allogeneic hematopoietic cell transplantation with pulmonary opacities, lung biopsy provided a diagnosis in 72% of procedures and altered management in 51%. Despite a 7% major complication rate, lung biopsy frequently clarified noninfectious etiologies when bronchoscopy was inconclusive.
Sergio Rodriguez‐Rodriguez   +8 more
wiley   +1 more source

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