Results 61 to 70 of about 77,284 (248)

Etiology and seasonality of viral respiratory infections in children under 5 years of age in Bucaramanga, Colombia

Iatreia, 2017
Objective: To describe viruses associated with respiratory infection in children in Bucaramanga, the main city in northeastern Colombia. Materials and methods: Descriptive study with prospective collection.
García-Corzo, Jorge Raúl, Niederbacher-Velásquez, Jurg, González-Rugeles, Clara, Rodríguez-Villamizar, Laura, Machuca-Pérez, Mayra, Torres-Prieto, Alexánder, Ortiz Rodríguez, Gloria, Romero-Salazar, Mónica   +7 more
doaj   +1 more source

Prevalence of respiratory viruses using polymerase chain reaction in children with wheezing, a systematic review and meta-analysis.

PLoS ONE, 2020
IntroductionWheezing is a major problem in children, and respiratory viruses are often believed to be the causative agent. While molecular detection tools enable identification of respiratory viruses in wheezing children, it remains unclear if and how ...
Cyprien Kengne-Nde, Sebastien Kenmoe, Abdou Fatawou Modiyinji, Richard Njouom   +3 more
doaj   +1 more source

Respiratory syncytial virus outbreak in a long-term care facility detected using reverse transcriptase polymerase chain reaction: an argument for real-time detection methods. [PDF]

, 2009
ObjectivesTo report an outbreak of respiratory synctyial virus (RSV) in a long-term care facility (LTCF) during ongoing routine respiratory illness surveillance.DesignRapid antigen testing, viral culture, direct fluorescent antibody (DFA) testing, and ...
Caram, L Brett, Chen, Jodi, Hillyard, David R, Petti, Cathy A, Polage, Christopher R, Schmader, Kenneth, She, Rosemary, Taggart, E William, Twersky, Jack, Woods, Christopher W   +9 more
core  

In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]

, 2007
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Bonnet, Marion, Deplanche, Martine, Lemaire, Mylène, Meyer, Gilles, Mirandette, Carole, Schelcher, François   +5 more
core   +1 more source

The role of viral interaction in household transmission of symptomatic influenza and respiratory syncytial virus

Nature Communications
The role of viral interaction—where one virus enhances or inhibits infection with another virus—in respiratory virus transmission is not well characterized.
Jessica C. Ibiebele, Elie-Tino Godonou, Amy P. Callear, Matthew R. Smith, Rachel Truscon, Emileigh Johnson, Marisa C. Eisenberg, Adam S. Lauring, Arnold S. Monto, Sarah Cobey, Emily T. Martin   +10 more
doaj   +1 more source

Performance of diagnostic tests to detect respiratory viruses in older adults. [PDF]

, 2010
The performance of 4 laboratory methods for diagnosis of viral respiratory tract infections (RTI) in older adults was evaluated. Seventy-four nasopharyngeal (NP) swab specimens were obtained from 60 patients with RTI at a long-term care facility over 2 ...
Caram, Lauren B, Hymas, Weston C, Petti, Cathy A, Polage, Christopher R, Schmader, Kenneth, She, Rosemary C, Taggart, Edward W, Woods, Christopher W   +7 more
core  

Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]

, 2014
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia, Castellano, Verónica, Gentile, Ángela, Grobaporto, Marcela, Juárez, María del Valle, Lucion, María Florencia, Mistchenko, Alicia Susana, Romanin, Viviana Sandra, Viegas, Mariana   +8 more
core   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium

Emerging Infectious Diseases
In a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation ...
Annabel Rector, Mandy Bloemen, Marijn Thijssen, Bram Pussig, Kurt Beuselinck, Marc Van Ranst, Elke Wollants   +6 more
doaj   +1 more source