Results 71 to 80 of about 2,090,908 (302)

The effect of problem based learning model in science process skills on respiratory system materials

open access: yesBiosfer
This research aims to determine the effect of problem-based learning (PBL) learning model on the science process skills (SPS) of grade XI students on respiratory system material.
Dliya Syahirah Eka Martin   +3 more
doaj   +1 more source

Respiratory and cardiac monitoring at night using a wrist wearable optical system

open access: yes, 2018
Sleep monitoring provides valuable insights into the general health of an individual and helps in the diagnostic of sleep-derived illnesses. Polysomnography, is considered the gold standard for such task.
Combertaldi, Selina   +8 more
core   +1 more source

Sweet syndrome with pulmonary involvement in a patient with myelodysplastic syndrome [PDF]

open access: yes, 2020
We report a patient with Sweet syndrome involving the pulmonary system in the context of myelodysplastic syndrome. Although Sweet syndrome may involve a variety of organ systems, the pulmonary system is rarely affected and can result in poor clinical ...
Bordelon, Jenna   +7 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

КЛИНИКО-ФУНКЦИОНАЛЬНЫЕ СОСТАВЛЯЮЩИЕ БРОНХОЛЕГОЧНОГО СИНДРОМА ПРИ ДИСПЛАЗИИ СОЕДИНИТЕЛЬНОЙ ТКАНИ

open access: yesАрхивъ внутренней медицины, 2015
To study the respiratory symptomatology in patients with connective tissue dysplasia (CTD) were surveyed 305 young people. Clinical and functional components of bronchopulmonary syndrome in CTD were identified through a comprehensive examination ...
М. В. Вершинина   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Association between preoperative oxygen reserve index and postoperative pulmonary complications: a prospective observational study [PDF]

open access: yesKorean Journal of Anesthesiology
Background The oxygen reserve index (ORi) noninvasively measures oxygen levels within the mild hyperoxia range. To evaluate whether a degree of increase in the ORi during preoxygenation for general anesthesia is associated with the occurrence of ...
Sangho Lee   +8 more
doaj   +1 more source

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

open access: yes, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

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