Results 91 to 100 of about 1,368,419 (314)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Respiratory System Effects of Search and Rescue Workers in the February 6 Kahramanmaraş Earthquakes [PDF]

European-Respiratory-Society Congress (ERS), SEP 07-11, 2024, Vienna, AUSTRIAEuropean Respirat ...
Gulhan, Pinar Yildiz, Balbay, Ege Gulec, Balbay, Oner Abidin, Arbak, Peri, Bayram, Hasan, Annakkaya, Ali Nihat   +5 more
core   +1 more source

European Respiratory Society guidelines for the management of adult bronchiectasis [PDF]

, 2017
Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult ...
Rohde, Gernot, Ruddy, Thomas,, Ringshausen, Felix C., Ruddy, Thomas, Subotic, Dragan, Welte, Tobias, Tonia, Thomy, Almagro, Marta,, A. De Soyza, Felix C. Ringshausen, Almagro, Marta, S. E. Marshall, Dimakou, Katerina,, Blasi, Francesco,, Loebinger, Michael R., Wilson, Robert, James D. Chalmers, Torres, Antoni,, Tobias Welte, Goeminne, Pieter C, A. Timothy, M. J. Mcdonnell, Chalmers, James D.,, Vendrell, Montserrat,, Elborn, J. Stuart, Chalmers, James D., Melissa J. McDonnell, Alan Timothy, Torres, Antoni, Eva Polverino, Goeminne, Pieter C.,, Cantón, Rafael, C. S. Haworth, F. Blasi, A. Torres, T. Welte, J. D. Chalmers, S. Aliberti, Goeminne, Pieter C., P. C. Goeminne, Hill, Adam T, Vilaró, Jordi, Murris, Marlene,, A. T. Hill, Montserrat Vendrell, Timothy, Alan,, Canton, Rafael,, Ställberg, Björn,, Aliberti, Stefano, S. Elborn, K. Dimakou, Chalmers, James D, M. Murris, Polverino, Eva, Stuart Elborn, Murris-Espin, Marlene, Bjorn Stallberg, Timothy, Alan, Haworth, Charles S, Welte, Tobias,, R. Wilson, M. Vendrell, Murris, Marlene, Adam T. Hill, Francesco Blasi, Rigau, David, Loebinger, Michael R, Ringshausen, Felix C, Hill, Adam T., Vendrell, Montserrat, D. Rigau, E. Polverino, Stefano Aliberti, Sara E. Marshall, Marlene Murris, Dragan Subotic, McDonnell, Melissa J.,, Pieter C. Goeminne, Marshall, Sara E.,, Marta Almagro, Dimakou, Katerina, M. R. Loebinger, Anthony De Soyza, Haworth, Charles S.,, J. Vilaró, M. Almagro, Aliberti, Stefano,, Marshall, Sara E., B. Stallberg, Polverino, Eva,, McDonnell, Melissa J., Antoni Torres, Subotic, Dragan,, Stallberg, Bjorn, Wilson, Robert,, Gernot Rohde, Loebinger, Michael R.,, Rafael Cantón, Elborn, Stuart,, Tonia, Thomy,, Blasi, Francesco, Elborn, Stuart, McDonnell, Melissa J, Hill, Adam T.,, Marshall, Sara E, De Soyza, Anthony, Thomy Tonia, David Rigau, Haworth, Charles S., T. Ruddy, Rohde, Gernot,, Jordi Vilaró, Robert Wilson, Ringshausen, Felix C.,, R. Cantón, D. Subotic, F. C. Ringshausen, Michael R. Loebinger, Katerina Dimakou, T. Tonia, Charles S. Haworth, Rigau, David,, G. Rohde, Thomas Ruddy, De Soyza, Anthony,, Vilaro, Jordi,   +125 more
core   +1 more source

An easy maneuver to screen for moderate-to-severe obstructive sleep spnea: the Simmons Chin Press and Tongue Curl [PDF]

Sleep Science
Objectives:: To demonstrate that the Simmons chin press and tongue curl (SCPTC) correlates with diagnosis of moderate-to-severe obstructive sleep apnea (msOSA) by itself as well as irrespective of the presence of other associated features ...
Gerard Joseph Meskill, Kelly Kincheloe, Jerald Howard Simmons, Sarah Dennis Meskill   +3 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Employment of combined-extraction from Argan oil and diluted apple cider vinegar (ACV-AO) for refuting pediculosis in cats

Kufa Journal for Veterinary Medical Sciences, 2017
The present study demonstrated a positive effect of both argan oil & apple cider vinegar mixed with pure water RO in the healing of head lice disease, as it was the best concentration plant is 50% and the level of significance p< 0.05 after adding Argan
Abdul-samad Uleiwi Hassan, Fawziyya Fakhry Al-Fayyadh, Yarob Sa'ad Abdul-Jaleel   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

A new estimator to minimize the error due to breathing in the measurement of respiratory impedance [PDF]

, 1988
This paper presents a new respiratory impedance estimator to minimize the error due to breathing. Its practical reliability was evaluated in a simulation using realistic signals.
Farré Ventura, Ramon, Peslin, René, Navajas Navarro, Daniel, Rotger i Estapé, Maria del Mar   +3 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source