Results 101 to 110 of about 28,018,362 (350)

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa, Pinkerton, Kent, Royer, Christopher, Schelegle, Edward   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Endocan and the respiratory system: a review

International Journal of COPD, 2016
Endocan, formerly called endothelial cell-specific molecule 1, is an endothelial cell-associated proteoglycan that is preferentially expressed by renal and pulmonary endothelium. It is upregulated by proangiogenic molecules as well as by pro-inflammatory
M. Kechagia, I. Papassotiriou, K. Gourgoulianis   +2 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Respiratory and cardiac monitoring at night using a wrist wearable optical system

, 2018
Sleep monitoring provides valuable insights into the general health of an individual and helps in the diagnostic of sleep-derived illnesses. Polysomnography, is considered the gold standard for such task.
Combertaldi, Selina, Dammeier, Franziska, Delgado-Gonzalo, Ricard, Kübler, Florian, Leeners, Brigitte, Lemkaddem, Alia, Rasch, Björn, Renevey, Philippe, Verjus, Christophe   +8 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Assessment of a Loop-Mediated Isothermal Amplification (LAMP) Assay for the Rapid Detection of Pathogenic Bacteria from Respiratory Samples in Patients with Hospital-Acquired Pneumonia

Microorganisms, 2020
Rapid identification of the causative agent of hospital-acquired pneumonia (HAP) will allow an earlier administration of a more appropriate antibiotic and could improve the outcome of these patients.
Andrea Vergara, Hervé Boutal, Adrián Ceccato, Míriam López, Adrià Cruells, Leticia Bueno-Freire, Javier Moreno-Morales, Jorge Puig de la Bellacasa, Pedro Castro, Antoni Torres, Francesc Marco, Climent Casals-Pascual, Jordi Vila   +12 more
doaj   +1 more source

ciliaFA : a research tool for automated, high-throughput measurement of ciliary beat frequency using freely available software [PDF]

, 2012
Background: Analysis of ciliary function for assessment of patients suspected of primary ciliary dyskinesia (PCD) and for research studies of respiratory and ependymal cilia requires assessment of both ciliary beat pattern and beat frequency.
C O’Callaghan, CL O’Callaghan, CM Smith, CW Wilson, EE Davis, G Mantovani, JH Sisson, JJ Ballenger, JR Kennedy, M Ryser, MA Chilvers, MA Chilvers, RA Hirst, RA Hirst, RA Hirst, S Dimova, TJ Mitchell, WA Stannard, WI Lee, WS Rasband   +19 more
core   +1 more source

Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function

Cell Stem Cell, 2014
Respiratory disease is the third leading cause of death in the industrialized world. Consequently, the trachea, lungs, and cardiopulmonary vasculature have been the focus of extensive investigations. Recent studies have provided new information about the
B. Hogan, C. E. Barkauskas, H. Chapman, J. Epstein, Rajan Jain, C. Hsia, L. Niklason, Elizabeth A. Calle, Andrew V Le, S. Randell, J. Rock, Melinda E. Snitow, M. Krummel, B. Stripp, Thiennu H. Vu, E. White, J. Whitsett, E. Morrisey   +17 more
semanticscholar   +1 more source

The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients

Journal of Medical Virology, 2020
Following the severe acute respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV), another highly pathogenic coronavirus named SARS‐CoV‐2 (previously known as 2019‐nCoV) emerged in December 2019 in Wuhan ...
Yan-Chao Li, W. Bai, T. Hashikawa
semanticscholar   +1 more source