Results 121 to 130 of about 1,368,419 (314)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Prevalence of microorganisms responsible for respiratory tract infections, Babol, 1997
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000 Objective: There is no doubt that causes of respiratory tract infections in ICU are very important. These organisms are one of the most important causes of mortality in ICU. Methods: In this cross-sectional study performed on all patients admitted in ICU
Kh Bidjani, K Aghchelli, M Arshi
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
, 1998 Annual; Electronic coverage as of Jan. 21, 2009: 1996/1997-; Description based on: 1996/1997; title from PDF p. [i] (viewed on Jan. 21, 2009).; Title from cover.; Report year runs July 1 through June 30.; Harvested from the web on 1/21 ...
Ohio Respiratory Care Board.
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Nasal concha with respiratory mucosa (dog, high magnification) [PDF]
, 2006 Stain: Hematoxylin and eosin. (↑) Indicates the transition of the olfactory epithelium (1) into the respiratory epithelium (2) with pseudostratified ciliated epithelium and goblet cells. The submucosa is richly vascularized (3).
Poels, Lambert G.
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ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Preliminary Analysis of Vital Proteins of the Human Respiratory Syncytial Virus [PDF]
, 2010 Human Respiratory Syncytial Virus infects the vast majority of children under the age of two and reoccurs in adulthood. It is a serious global problem as severe infection and death can result in the very young or very old and in immunocompromised people.
BACHE, HELEN,CLARE
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Toxicology of the respiratory system
Folia Pharmacologica Japonica, 2009 呼吸器は，空気から酸素を取り入れ血液から二酸化炭素を放出するガス交換を行うための器官である．空気中に存在す化学物質は呼吸を通して体内に入るため，呼吸器はこれらの化学物質に最初に接触しその影響を最も受けやすい器官である．このため，大気汚染物質による健康障害では呼吸器が標的器官となることが多い．医薬品の分野では，吸入以外の経路でも抗癌剤等による薬剤性肺障害の報告があり，本誌でも詳しい総説がある（1）．また，近年は経鼻投与など経気道的に投与する薬剤の実用化が進んでおり，医薬品の開発に際して鼻腔などの気道を含む呼吸器への直接的な接触による副作用が課題になってきている．本稿では，鼻腔等の気道を中心として，呼吸器の構造と機能，呼吸器毒性の検査法，薬剤等による呼吸器毒性について概説する．
openaire +3 more sources