Results 61 to 70 of about 21,337,282 (283)

Solunum sistemi hastalığı olan çocuk ve ergenlerde psikiyatrik bozukluk ve belirtiler

Genel Tıp Dergisi, 2015
Solunum sistemi hastalıkları bireyi fiziksel, duygusal ve sosyal yönden etkileyen ve hastaların sosyal destek gereksinimlerinin art- masına neden olan önemli hastalıklardır.
Serhat Türkoğlu
doaj  

Case Report: All That Glisters Is Not* Cancer

Frontiers in Medicine, 2020
Properly performed staging in non-small-cell lung cancer (NSCLC) is necessary to avoid wrong therapeutic decisions. Here we present a case which manifested as advanced NSCLC but ultimately was composed of two different and rare pathologies.
Claudio Tirelli, Chandra Bortolotto, Patrizia Morbini, Giulia Maria Stella   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Expert System for Diagnosing Respiratory Diseases for Cats

Jurnal Riset Informatika
Cats are the most common pet in Indonesia with a cat ownership rate of 47% (Rakuten Insight, 2021). Cat owners need to know and recognize the signs and symptoms of the diseases that often occur in cats, especially respiratory problems and diseases ...
Fitria Adyati Mardha, Ria Astriratma, Muhammad Panji Muslim   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Application of Endoscope in Elderly Respiratory System Diseases

Guoji laonian yixue zazhi
Respiratory system disease has always been at a high morbidity and mortality rate in elderly patients.Endoscopic technology is playing an increasingly important role in the treatment of respiratory system disease in elderly patients.With the increase of ...
Shuang Gu
doaj   +1 more source

The respiratory neuromuscular system in Pompe disease [PDF]

Respiratory Physiology & Neurobiology, 2013
Pompe disease is due to mutations in the gene encoding the lysosomal enzyme acid α-glucosidase (GAA). Absence of functional GAA typically results in cardiorespiratory failure in the first year; reduced GAA activity is associated with progressive respiratory failure later in life.
David D, Fuller, Mai K, ElMallah, Barbara K, Smith, Manuela, Corti, Lee Ann, Lawson, Darin J, Falk, Barry J, Byrne   +6 more
openaire   +3 more sources

Respiratory manifestations in patients with inherited metabolic diseases [PDF]

, 2013
Growing evidence indicates that inherited metabolic diseases are increasingly being recognised. Life expectancy for many patients is progressively improving because new therapeutic strategies are available.
Montella, Silvia, De Stefano, Sara, Silvia Montella, Francesca Santamaria, Mirra, Virginia, Generoso Andria, Giancarlo Parenti, SANTAMARIA, FRANCESCA, PARENTI, GIANCARLO, Virginia Mirra, Sara De Stefano, ANDRIA, GENEROSO   +11 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source